2cal
From Proteopedia
(New page: 200px<br /> <applet load="2cal" size="450" color="white" frame="true" align="right" spinBox="true" caption="2cal, resolution 1.10Å" /> '''CRYSTAL STRUCTURE O...) |
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==About this Structure== | ==About this Structure== | ||
| - | 2CAL is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/ | + | 2CAL is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Acidithiobacillus_ferrooxidans Acidithiobacillus ferrooxidans]] with CU1 as [[http://en.wikipedia.org/wiki/ligand ligand]]. Structure known Active Site: AC1. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=2CAL OCA]]. |
==Reference== | ==Reference== | ||
Atomic resolution crystal structures, EXAFS, and quantum chemical studies of rusticyanin and its two mutants provide insight into its unusual properties., Barrett ML, Harvey I, Sundararajan M, Surendran R, Hall JF, Ellis MJ, Hough MA, Strange RW, Hillier IH, Hasnain SS, Biochemistry. 2006 Mar 7;45(9):2927-39. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=16503647 16503647] | Atomic resolution crystal structures, EXAFS, and quantum chemical studies of rusticyanin and its two mutants provide insight into its unusual properties., Barrett ML, Harvey I, Sundararajan M, Surendran R, Hall JF, Ellis MJ, Hough MA, Strange RW, Hillier IH, Hasnain SS, Biochemistry. 2006 Mar 7;45(9):2927-39. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=16503647 16503647] | ||
| + | [[Category: Acidithiobacillus ferrooxidans]] | ||
[[Category: Single protein]] | [[Category: Single protein]] | ||
| - | [[Category: Thiobacillus ferrooxidans]] | ||
[[Category: Barrett, M.L.]] | [[Category: Barrett, M.L.]] | ||
[[Category: Ellis, M.J.]] | [[Category: Ellis, M.J.]] | ||
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[[Category: transport]] | [[Category: transport]] | ||
| - | ''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Tue Oct 30 14:31:52 2007'' |
Revision as of 12:27, 30 October 2007
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CRYSTAL STRUCTURE OF HIS143MET RUSTICYANIN
Overview
Rusticyanin from the extremophile Thiobacillus ferrooxidans is a blue, copper protein with unusually high redox potential and acid stability. We, present the crystal structures of native rusticyanin and of its Cu site, mutant His143Met at 1.27 and 1.10 A, respectively. The very high, resolution of these structures allows a direct comparison with EXAFS data, and with quantum chemical models of the oxidized and reduced forms of the, proteins, based upon both isolated and embedded clusters and density, functional theory (DFT) methods. We further predict the structure of the, Cu(II) form of the His143Met mutant which has been experimentally, inaccessible due to its very high redox potential. We also present, metrical EXAFS data and quantum chemical calculations for the oxidized and, reduced ... [(full description)]
About this Structure
2CAL is a [Single protein] structure of sequence from [Acidithiobacillus ferrooxidans] with CU1 as [ligand]. Structure known Active Site: AC1. Full crystallographic information is available from [OCA].
Reference
Atomic resolution crystal structures, EXAFS, and quantum chemical studies of rusticyanin and its two mutants provide insight into its unusual properties., Barrett ML, Harvey I, Sundararajan M, Surendran R, Hall JF, Ellis MJ, Hough MA, Strange RW, Hillier IH, Hasnain SS, Biochemistry. 2006 Mar 7;45(9):2927-39. PMID:16503647
Page seeded by OCA on Tue Oct 30 14:31:52 2007
Categories: Acidithiobacillus ferrooxidans | Single protein | Barrett, M.L. | Ellis, M.J. | Hall, J.F. | Harvey, I. | Hasnain, S.S. | Hillier, I. | Hough, M.A. | Strange, R.W. | Sundararajan, M. | Surendran, R. | CU1 | Blue copper protein | Copper | Electron transport | Iron respiratory electron transport chain | Metal-binding | Periplasmic | Rusticyanin | Transport
