3d4n
From Proteopedia
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===Crystal Structure of Human 11-beta-Hydroxysteroid Dehydrogenase (HSD1) in Complex with Sulfonamide Inhibitor=== | ===Crystal Structure of Human 11-beta-Hydroxysteroid Dehydrogenase (HSD1) in Complex with Sulfonamide Inhibitor=== | ||
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==About this Structure== | ==About this Structure== | ||
| - | + | [[3d4n]] is a 4 chain structure of [[Hydroxysteroid dehydrogenase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3D4N OCA]. | |
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| + | ==See Also== | ||
| + | *[[Hydroxysteroid dehydrogenase|Hydroxysteroid dehydrogenase]] | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:018553955</ref><references group="xtra"/> |
[[Category: 11-beta-hydroxysteroid dehydrogenase]] | [[Category: 11-beta-hydroxysteroid dehydrogenase]] | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
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[[Category: Nadp]] | [[Category: Nadp]] | ||
[[Category: Oxidoreductase]] | [[Category: Oxidoreductase]] | ||
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[[Category: Signal-anchor]] | [[Category: Signal-anchor]] | ||
[[Category: Steroid metabolism]] | [[Category: Steroid metabolism]] | ||
[[Category: Transmembrane]] | [[Category: Transmembrane]] | ||
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Revision as of 16:26, 27 July 2012
Contents |
Crystal Structure of Human 11-beta-Hydroxysteroid Dehydrogenase (HSD1) in Complex with Sulfonamide Inhibitor
Template:ABSTRACT PUBMED 18553955
About this Structure
3d4n is a 4 chain structure of Hydroxysteroid dehydrogenase with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Julian LD, Wang Z, Bostick T, Caille S, Choi R, Degraffenreid M, Di Y, He X, Hungate RW, Jaen JC, Liu J, Monshouwer M, McMinn D, Rew Y, Sudom A, Sun D, Tu H, Ursu S, Walker N, Yan X, Ye Q, Powers JP. Discovery of Novel, Potent Benzamide Inhibitors of 11beta-Hydroxysteroid Dehydrogenase Type 1 (11beta-HSD1) Exhibiting Oral Activity in an Enzyme Inhibition ex Vivo Model. J Med Chem. 2008 Jun 14;. PMID:18553955 doi:http://dx.doi.org/10.1021/jm800310g
Categories: 11-beta-hydroxysteroid dehydrogenase | Homo sapiens | Liu, J. | Sudom, A. | Walker, N P. | Wang, Z. | 11beta | Dehydrogenase | Endoplasmic reticulum | Glycoprotein | Hydroxysteroid | Lipid metabolism | Membrane | Microsome | Nadp | Oxidoreductase | Signal-anchor | Steroid metabolism | Transmembrane
