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==Myosin 2 Motor Domain==
==Myosin 2 Motor Domain==
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Myosin is a protein known largely for it's involvement in the contraction of the body's muscles. However, this protein can also be found in the ears and eyes, blood platelets, and it has functions in cytokinesis.
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Myosin II is found in the myofibers of skeletal, smooth, and cardiac muscle tissue where the protein forms the thick filaments. The myosin of the thick filaments has the ability to bind the thin filaments, composed of actin. The myosin head then rotates and pulls the two filaments past one another providing the basis for muscle contraction.
This is the <scene name='Sandbox10/Newscene/1'>active site</scene> of the protein.
This is the <scene name='Sandbox10/Newscene/1'>active site</scene> of the protein.

Revision as of 15:22, 2 March 2009

This sandbox is in use until June 1, 2009 for UMass Chemistry 490a. Others please do not edit this page. Thanks! Brendan Jones

Myosin 2 Motor Domain

Myosin is a protein known largely for it's involvement in the contraction of the body's muscles. However, this protein can also be found in the ears and eyes, blood platelets, and it has functions in cytokinesis.

Myosin II is found in the myofibers of skeletal, smooth, and cardiac muscle tissue where the protein forms the thick filaments. The myosin of the thick filaments has the ability to bind the thin filaments, composed of actin. The myosin head then rotates and pulls the two filaments past one another providing the basis for muscle contraction.

This is the of the protein.


Thanks to Fedorov, R., Boehl, M., Tsiavaliaris, G., Hartmann, F.K., Baruch, P., Brenner, B., Martin, R., Knoelker, H.J., Gutzeit, H.O., Manstein, D.J. for their work in resolving the structure of this protein.


PDB ID 2jhr

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2jhr, resolution 2.80Å ()
Ligands: , ,
Related: 1mne, 1d1c, 1jx2, 1q5g, 1w9l, 1vom, 1d0y, 1mmn, 2aka, 1lvk, 1w9j, 1jwy, 1yv3, 1fmv, 1fmw, 1d0x, 1d1b, 1g8x, 1mma, 1d1a, 1mmg, 1w9i, 1d0z, 1mnd, 1w9k, 1mmd, 2jj9
Resources: FirstGlance, OCA, PDBsum, RCSB
Coordinates: save as pdb, mmCIF, xml


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