Sandbox13
From Proteopedia
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==About this Structure== | ==About this Structure== | ||
| - | This is the protein Human Serum Albumin(HSA),it has alpha helices (shown in red) and also beta sheets (shown in blue), now the hydrophobic parts of HSA are on both the surface and inside. HSA is an abundant transport protein found in plasma that binds a wide variety of drugs in two primary binding sites (I and II) and can have a significant impact on their pharmacokinetics. | + | This is the protein Human Serum Albumin(HSA),it has <scene name='Sandbox13/Alpha_helices/1'>alpha helices</scene> (shown in red) and also <scene name='Sandbox13/Beta_sheets/1'>beta sheets</scene> (shown in blue), now the <scene name='Sandbox13/Hydrophobic/1'>hydrophobic</scene> parts of HSA are on both the surface and inside. HSA is an abundant transport protein found in plasma that binds a wide variety of drugs in two primary binding sites (I and II) and can have a significant impact on their pharmacokinetics. |
Reference: Crystal structure analysis of warfarin binding to human serum albumin: anatomy of drug site I.,Petitpas, I., Bhattacharya, A.A., Twine, S., East, M., Curry, S., VJ.Biol.Chem. v276 pp. 22804-9, 2001 | Reference: Crystal structure analysis of warfarin binding to human serum albumin: anatomy of drug site I.,Petitpas, I., Bhattacharya, A.A., Twine, S., East, M., Curry, S., VJ.Biol.Chem. v276 pp. 22804-9, 2001 | ||
Revision as of 15:05, 4 March 2009
This sandbox is in use until June 1, 2009 for UMass Chemistry 490a. Others please do not edit this page. Thanks!
Quoc Hung Pham 3/3/09
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Name
Human Serum Albumin
About this Structure
This is the protein Human Serum Albumin(HSA),it has (shown in red) and also (shown in blue), now the parts of HSA are on both the surface and inside. HSA is an abundant transport protein found in plasma that binds a wide variety of drugs in two primary binding sites (I and II) and can have a significant impact on their pharmacokinetics.
Reference: Crystal structure analysis of warfarin binding to human serum albumin: anatomy of drug site I.,Petitpas, I., Bhattacharya, A.A., Twine, S., East, M., Curry, S., VJ.Biol.Chem. v276 pp. 22804-9, 2001
