We apologize for Proteopedia being slow to respond. For the past two years, a new implementation of Proteopedia has been being built. Soon, it will replace this 18-year old system. All existing content will be moved to the new system at a date that will be announced here.

2j03

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
(New page: 200px<br /><applet load="2j03" size="450" color="white" frame="true" align="right" spinBox="true" caption="2j03, resolution 2.8&Aring;" /> '''STRUCTURE OF THE THER...)
Line 1: Line 1:
-
[[Image:2j03.gif|left|200px]]<br /><applet load="2j03" size="450" color="white" frame="true" align="right" spinBox="true"
+
[[Image:2j03.gif|left|200px]]<br /><applet load="2j03" size="350" color="white" frame="true" align="right" spinBox="true"
caption="2j03, resolution 2.8&Aring;" />
caption="2j03, resolution 2.8&Aring;" />
'''STRUCTURE OF THE THERMUS THERMOPHILUS 70S RIBOSOME COMPLEXED WITH MRNA, TRNA AND PAROMOMYCIN (PART 4 OF 4). THIS FILE CONTAINS THE 50S SUBUNIT FROM MOLECULE II.'''<br />
'''STRUCTURE OF THE THERMUS THERMOPHILUS 70S RIBOSOME COMPLEXED WITH MRNA, TRNA AND PAROMOMYCIN (PART 4 OF 4). THIS FILE CONTAINS THE 50S SUBUNIT FROM MOLECULE II.'''<br />
==Overview==
==Overview==
-
The crystal structure of the bacterial 70S ribosome refined to 2.8, angstrom resolution reveals atomic details of its interactions with, messenger RNA (mRNA) and transfer RNA (tRNA). A metal ion stabilizes a, kink in the mRNA that demarcates the boundary between A and P sites, which, is potentially important to prevent slippage of mRNA. Metal ions also, stabilize the intersubunit interface. The interactions of E-site tRNA with, the 50S subunit have both similarities and differences compared to those, in the archaeal ribosome. The structure also rationalizes much biochemical, and genetic data on translation.
+
The crystal structure of the bacterial 70S ribosome refined to 2.8 angstrom resolution reveals atomic details of its interactions with messenger RNA (mRNA) and transfer RNA (tRNA). A metal ion stabilizes a kink in the mRNA that demarcates the boundary between A and P sites, which is potentially important to prevent slippage of mRNA. Metal ions also stabilize the intersubunit interface. The interactions of E-site tRNA with the 50S subunit have both similarities and differences compared to those in the archaeal ribosome. The structure also rationalizes much biochemical and genetic data on translation.
==About this Structure==
==About this Structure==
-
2J03 is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus] with LYS as [http://en.wikipedia.org/wiki/ligand ligand]. Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=2J03 OCA].
+
2J03 is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus] with <scene name='pdbligand=LYS:'>LYS</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2J03 OCA].
==Reference==
==Reference==
Line 13: Line 13:
[[Category: Protein complex]]
[[Category: Protein complex]]
[[Category: Thermus thermophilus]]
[[Category: Thermus thermophilus]]
-
[[Category: Dunham, C.M.]]
+
[[Category: Dunham, C M.]]
-
[[Category: Kelley, A.C.]]
+
[[Category: Kelley, A C.]]
-
[[Category: Murphy, F.V.]]
+
[[Category: Murphy, F V.]]
[[Category: Petry, S.]]
[[Category: Petry, S.]]
[[Category: Ramakrishnan, V.]]
[[Category: Ramakrishnan, V.]]
[[Category: Selmer, M.]]
[[Category: Selmer, M.]]
-
[[Category: Weir, J.R.]]
+
[[Category: Weir, J R.]]
[[Category: Weixlbaumer, A.]]
[[Category: Weixlbaumer, A.]]
[[Category: LYS]]
[[Category: LYS]]
Line 28: Line 28:
[[Category: trna]]
[[Category: trna]]
-
''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Wed Nov 21 12:30:19 2007''
+
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 17:57:57 2008''

Revision as of 15:57, 21 February 2008

Image:2j03.gif

2j03, resolution 2.8Å

Drag the structure with the mouse to rotate

STRUCTURE OF THE THERMUS THERMOPHILUS 70S RIBOSOME COMPLEXED WITH MRNA, TRNA AND PAROMOMYCIN (PART 4 OF 4). THIS FILE CONTAINS THE 50S SUBUNIT FROM MOLECULE II.

Overview

The crystal structure of the bacterial 70S ribosome refined to 2.8 angstrom resolution reveals atomic details of its interactions with messenger RNA (mRNA) and transfer RNA (tRNA). A metal ion stabilizes a kink in the mRNA that demarcates the boundary between A and P sites, which is potentially important to prevent slippage of mRNA. Metal ions also stabilize the intersubunit interface. The interactions of E-site tRNA with the 50S subunit have both similarities and differences compared to those in the archaeal ribosome. The structure also rationalizes much biochemical and genetic data on translation.

About this Structure

2J03 is a Protein complex structure of sequences from Thermus thermophilus with as ligand. Full crystallographic information is available from OCA.

Reference

Structure of the 70S ribosome complexed with mRNA and tRNA., Selmer M, Dunham CM, Murphy FV 4th, Weixlbaumer A, Petry S, Kelley AC, Weir JR, Ramakrishnan V, Science. 2006 Sep 29;313(5795):1935-42. Epub 2006 Sep 7. PMID:16959973

Page seeded by OCA on Thu Feb 21 17:57:57 2008

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/2j03"
Personal tools