3dpe
From Proteopedia
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==About this Structure== | ==About this Structure== | ||
| - | + | [[3dpe]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DPE OCA]. | |
==Reference== | ==Reference== | ||
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[[Category: Zinc]] | [[Category: Zinc]] | ||
[[Category: Zymogen]] | [[Category: Zymogen]] | ||
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| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Mar 4 14:48:35 2009'' | ||
Revision as of 18:23, 14 March 2011
Crystal structure of the complex between MMP-8 and a non-zinc chelating inhibitor
Template:ABSTRACT PUBMED 19173605
About this Structure
3dpe is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Pochetti G, Montanari R, Gege C, Chevrier C, Taveras AG, Mazza F. Extra Binding Region Induced by Non-Zinc Chelating Inhibitors into the S(1)' Subsite of Matrix Metalloproteinase 8 (MMP-8) (dagger). J Med Chem. 2009 Jan 27. PMID:19173605 doi:http://dx.doi.org/10.1021/jm801166j
- Wasserman ZR. Making a new turn in matrix metalloprotease inhibition. Chem Biol. 2005 Feb;12(2):143-4. PMID:15734640 doi:http://dx.doi.org/10.1016/j.chembiol.2005.01.008
- Johnson AR, Pavlovsky AG, Ortwine DF, Prior F, Man CF, Bornemeier DA, Banotai CA, Mueller WT, McConnell P, Yan C, Baragi V, Lesch C, Roark WH, Wilson M, Datta K, Guzman R, Han HK, Dyer RD. Discovery and characterization of a novel inhibitor of matrix metalloprotease-13 that reduces cartilage damage in vivo without joint fibroplasia side effects. J Biol Chem. 2007 Sep 21;282(38):27781-91. Epub 2007 Jul 10. PMID:17623656 doi:http://dx.doi.org/10.1074/jbc.M703286200
- Morales R, Perrier S, Florent JM, Beltra J, Dufour S, De Mendez I, Manceau P, Tertre A, Moreau F, Compere D, Dublanchet AC, O'Gara M. Crystal structures of novel non-peptidic, non-zinc chelating inhibitors bound to MMP-12. J Mol Biol. 2004 Aug 20;341(4):1063-76. PMID:15289103 doi:http://dx.doi.org/10.1016/j.jmb.2004.06.039
Categories: Homo sapiens | Neutrophil collagenase | Mazza, F. | Montanari, R. | Pochetti, G. | Calcium | Collagen degradation | Extracellular matrix | Glycoprotein | Hydrolase | Metal-binding | Metalloprotease | Non-zinc chelating inhibitor | Polymorphism | Protease | Secreted | Selective inhibition | Zinc | Zymogen
