Sandbox13
From Proteopedia
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==About this Structure== | ==About this Structure== | ||
| - | This is the | + | This is the Human Serum Albumin(HSA),it has <scene name='Sandbox13/Alpha_helices/1'>alpha helices</scene> (shown in red), <scene name='Sandbox13/Beta_sheets/1'>beta sheets</scene> (shown in blue), and the <scene name='Sandbox13/Hydrophobic/1'>hydrophobic</scene> parts. HSA is an abundant transport protein found in plasma that binds a wide variety of drugs in two primary binding sites (I and II) and can have a significant impact on their pharmacokinetics. |
Reference: Crystal structure analysis of warfarin binding to human serum albumin: anatomy of drug site I.,Petitpas, I., Bhattacharya, A.A., Twine, S., East, M., Curry, S., VJ.Biol.Chem. v276 pp. 22804-9, 2001 | Reference: Crystal structure analysis of warfarin binding to human serum albumin: anatomy of drug site I.,Petitpas, I., Bhattacharya, A.A., Twine, S., East, M., Curry, S., VJ.Biol.Chem. v276 pp. 22804-9, 2001 | ||
Revision as of 15:07, 4 March 2009
This sandbox is in use until June 1, 2009 for UMass Chemistry 490a. Others please do not edit this page. Thanks!
Quoc Hung Pham 3/3/09
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Name
Human Serum Albumin
About this Structure
This is the Human Serum Albumin(HSA),it has (shown in red), (shown in blue), and the parts. HSA is an abundant transport protein found in plasma that binds a wide variety of drugs in two primary binding sites (I and II) and can have a significant impact on their pharmacokinetics.
Reference: Crystal structure analysis of warfarin binding to human serum albumin: anatomy of drug site I.,Petitpas, I., Bhattacharya, A.A., Twine, S., East, M., Curry, S., VJ.Biol.Chem. v276 pp. 22804-9, 2001
