3dds

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{{ABSTRACT_PUBMED_19138846}}
{{ABSTRACT_PUBMED_19138846}}
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==Disease==
 
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Known disease associated with this structure: Glycogen storage disease VI OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=232700 232700]]
 
==About this Structure==
==About this Structure==
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3DDS is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DDS OCA].
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3DDS is a 2 chains structure with sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DDS OCA].
==Reference==
==Reference==
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Anthranilimide based glycogen phosphorylase inhibitors for the treatment of type 2 diabetes. Part 3: X-ray crystallographic characterization, core and urea optimization and in vivo efficacy., Thomson SA, Banker P, Bickett DM, Boucheron JA, Carter HL, Clancy DC, Cooper JP, Dickerson SH, Garrido DM, Nolte RT, Peat AJ, Sheckler LR, Sparks SM, Tavares FX, Wang L, Wang TY, Weiel JE, Bioorg Med Chem Lett. 2008 Dec 25. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/19138846 19138846]
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<ref group="xtra">PMID:19138846</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Phosphorylase]]
[[Category: Phosphorylase]]
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[[Category: Single protein]]
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[[Category: Nolte, R T.]]
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[[Category: Pdbx_ordinal=, <PDBx:audit_author.]]
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[[Category: Acetylation]]
[[Category: Acetylation]]
[[Category: Allosteric enzyme]]
[[Category: Allosteric enzyme]]
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[[Category: Transferase]]
[[Category: Transferase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Mar 4 20:12:24 2009''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Sep 22 11:59:22 2010''

Revision as of 08:50, 22 September 2010

Image:3dds.png

Template:STRUCTURE 3dds

Crystal structure of glycogen phosphorylase complexed with an anthranilimide based inhibitor GSK261

Template:ABSTRACT PUBMED 19138846

About this Structure

3DDS is a 2 chains structure with sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Thomson SA, Banker P, Bickett DM, Boucheron JA, Carter HL, Clancy DC, Cooper JP, Dickerson SH, Garrido DM, Nolte RT, Peat AJ, Sheckler LR, Sparks SM, Tavares FX, Wang L, Wang TY, Weiel JE. Anthranilimide based glycogen phosphorylase inhibitors for the treatment of type 2 diabetes. Part 3: X-ray crystallographic characterization, core and urea optimization and in vivo efficacy. Bioorg Med Chem Lett. 2009 Feb 15;19(4):1177-82. Epub 2008 Dec 25. PMID:19138846 doi:10.1016/j.bmcl.2008.12.085

Page seeded by OCA on Wed Sep 22 11:59:22 2010

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