1qnx
From Proteopedia
(New page: 200px<br /> <applet load="1qnx" size="450" color="white" frame="true" align="right" spinBox="true" caption="1qnx, resolution 1.90Å" /> '''VES V 5, AN ALLERGE...) |
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==About this Structure== | ==About this Structure== | ||
| - | 1QNX is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Vespula_vulgaris Vespula vulgaris]] with NA as [[http://en.wikipedia.org/wiki/ligand ligand]]. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1QNX OCA]]. | + | 1QNX is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Vespula_vulgaris Vespula vulgaris]] with NA as [[http://en.wikipedia.org/wiki/ligand ligand]]. Structure known Active Site: NA1. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1QNX OCA]]. |
==Reference== | ==Reference== | ||
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[[Category: vespid venom]] | [[Category: vespid venom]] | ||
| - | ''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Tue Oct 30 14:34:15 2007'' |
Revision as of 12:29, 30 October 2007
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VES V 5, AN ALLERGEN FROM VESPULA VULGARIS VENOM
Overview
Ves v 5 is one of three major allergens found in yellow-jacket venom:, phospholipase A(1) (Ves v 1), hyaluronidase (Ves v 2), and antigen 5 (Ves, v 5). Ves v 5 is related by high amino acid sequence identity to, pathogenesis-related proteins including proteins from mammals, reptiles, insects, fungi, and plants. The crystal structure of Ves v 5 has been, solved and refined to a resolution of 1.9 A. The majority of residues, conserved between the pathogenesis-related proteins can be rationalized in, terms of hydrogen bonding patterns and hydrophobic interactions defining, an alpha-beta-alpha sandwich core structure. A small number of consensus, residues are solvent exposed (including two adjacent histidines) and, located in an elongated cavity that forms a putative active site. The site, ... [(full description)]
About this Structure
1QNX is a [Single protein] structure of sequence from [Vespula vulgaris] with NA as [ligand]. Structure known Active Site: NA1. Full crystallographic information is available from [OCA].
Reference
Major venom allergen of yellow jackets, Ves v 5: structural characterization of a pathogenesis-related protein superfamily., Henriksen A, King TP, Mirza O, Monsalve RI, Meno K, Ipsen H, Larsen JN, Gajhede M, Spangfort MD, Proteins. 2001 Dec 1;45(4):438-48. PMID:11746691
Page seeded by OCA on Tue Oct 30 14:34:15 2007
