Triose Phosphate Isomerase
From Proteopedia
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== Disease == | == Disease == | ||
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=== Triose Phosphate Isomerase Deficiency === | === Triose Phosphate Isomerase Deficiency === | ||
| - | Triose Phosphate Isomease Deficiency is a rare (less then 100 cases worldwide), autosomal recessive disorder first described in 1965.<Schneider, Arthur S.; William N. Valentine, Hattori M, H. L. Heins Jr (1965). "Hereditary Hemolytic Anemia with Triosephosphate Isomerase Deficiency". New England Journal of Medicine 272: 229–35> Symptoms include haemolytic anaemia, cardiomyopathy, an increased susceptibility to infections, severe neurological dysfunctions, and, often times, death in early childhood. | ||
== See Also == | == See Also == | ||
== References == | == References == | ||
Revision as of 22:31, 18 March 2009
Triose Phosphate Isomerase (TPI or TIM) which catalyzes the reversible interconversion of the triose phosphate isomers dihydroxyacetone phosphate and D-glyceraldehyde-3-phosphate, an essential process in the glycolytic pathway.
Contents |
Mechanism
Acid Base Catalysis
Diagram .<ref name= "web.virginia.edu" [1]
Structure & Function
Disease
Triose Phosphate Isomerase Deficiency
See Also
References
Proteopedia Page Contributors and Editors (what is this?)
Gregg Snider, Eric Martz, Michal Harel, Alexander Berchansky, David Canner, Eran Hodis, Stephen Everse, Angel Herraez, Jane S. Richardson
![[1]](http://web.virginia.edu/Heidi/chapter19/Images/8883n19_15.jpg){kind=link}