Triose Phosphate Isomerase
From Proteopedia
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== Structure & Function == | == Structure & Function == | ||
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== Disease == | == Disease == | ||
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=== Triose Phosphate Isomerase Deficiency === | === Triose Phosphate Isomerase Deficiency === | ||
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== See Also == | == See Also == | ||
Revision as of 00:32, 20 March 2009
'Triose Phosphate Isomerase
Overview
(TPI or TIM) which catalyzes the reversible interconversion of the triose phosphate isomers dihydroxyacetone phosphate and D-glyceraldehyde-3-phosphate, an essential process in the glycolytic pathway.
Mechanism
TPI catalyzes the transfer of a hydrogen atom from carbon 1 to carbon 2, an intramolecular oxidation-reduction. This isomerization of a ketose to an aldose proceeds through an enediol intermediate.<Biochemistry 6th Edition>
Acid Base Catalysis
Diagram .[1]
Proteopedia Page Contributors and Editors (what is this?)
Gregg Snider, Eric Martz, Michal Harel, Alexander Berchansky, David Canner, Eran Hodis, Stephen Everse, Angel Herraez, Jane S. Richardson
