3b2v
From Proteopedia
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{{ABSTRACT_PUBMED_18275813}} | {{ABSTRACT_PUBMED_18275813}} | ||
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| - | ==Disease== | ||
| - | Known disease associated with this structure: Adenocarcinoma of lung, response to tyrosine kinase inhibitor in OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=131550 131550]], Nonsmall cell lung cancer, response to tyrosine kinase inhibitor in OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=131550 131550]], Nonsmall cell lung cancer, susceptibility to OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=131550 131550]] | ||
==About this Structure== | ==About this Structure== | ||
| - | + | [[3b2v]] is a 3 chain structure of [[Epidermal Growth Factor Receptor]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3B2V OCA]. | |
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| + | ==See Also== | ||
| + | *[[Epidermal Growth Factor Receptor]] | ||
==Reference== | ==Reference== | ||
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[[Category: Tyrosine-protein kinase]] | [[Category: Tyrosine-protein kinase]] | ||
[[Category: Ubl conjugation]] | [[Category: Ubl conjugation]] | ||
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| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 22 10:49:49 2009'' | ||
Revision as of 02:29, 27 December 2010
Contents |
Crystal structure of the extracellular region of the epidermal growth factor receptor in complex with the Fab fragment of IMC-11F8
Template:ABSTRACT PUBMED 18275813
About this Structure
3b2v is a 3 chain structure of Epidermal Growth Factor Receptor with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Li S, Kussie P, Ferguson KM. Structural basis for EGF receptor inhibition by the therapeutic antibody IMC-11F8. Structure. 2008 Feb;16(2):216-27. PMID:18275813 doi:10.1016/j.str.2007.11.009
Categories: Homo sapiens | Receptor protein-tyrosine kinase | Ferguson, K M. | Kussie, P. | Li, S. | Alternative splicing | Anti-oncogene | Antigen:antibody complex | Antitumor | Atp-binding | Cell cycle | Cell surface receptor | Disease mutation | Drug | Fab fragment | Glycoprotein | Immune system/transferase complex | Kinase | Membrane | Nucleotide-binding | Phosphoprotein | Polymorphism | Secreted | Transferase | Transmembrane | Tyrosine-protein kinase | Ubl conjugation
