2wcx

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(New page: '''Unreleased structure''' The entry 2wcx is ON HOLD Authors: DiMarco, S. Description: Crystal Structure of Hepatitis C Virus NS5B Polymerase in Complex with Thienopyrrole-Based Finger...)
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'''Unreleased structure'''
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[[Image:2wcx.jpg|left|200px]]
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The entry 2wcx is ON HOLD
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{{STRUCTURE_2wcx| PDB=2wcx | SCENE= }}
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Authors: DiMarco, S.
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===CRYSTAL STRUCTURE OF HEPATITIS C VIRUS NS5B POLYMERASE IN COMPLEX WITH THIENOPYRROLE-BASED FINGER-LOOP INHIBITORS===
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Description: Crystal Structure of Hepatitis C Virus NS5B Polymerase in Complex with Thienopyrrole-Based Finger-Loop Inhibitors
 
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Mar 25 12:04:04 2009''
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==About this Structure==
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2WCX is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Hepatitis_c_virus Hepatitis c virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WCX OCA].
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==Reference==
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<ref group="xtra">PMID:15955819</ref><references group="xtra"/>
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[[Category: Hepatitis c virus]]
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[[Category: RNA-directed RNA polymerase]]
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[[Category: Marco, S Di.]]
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[[Category: Allosteric inhibitor]]
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[[Category: Atp-binding]]
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[[Category: Envelope protein]]
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[[Category: Genotype 1b]]
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[[Category: Hcv]]
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[[Category: Helicase]]
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[[Category: Hepatitis c virus]]
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[[Category: Hydrolase]]
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[[Category: Membrane]]
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[[Category: Nni]]
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[[Category: Non nucleoside inhibitor]]
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[[Category: Ns5b]]
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[[Category: Nucleotide-binding]]
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[[Category: Polymerase]]
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[[Category: Rna replication]]
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[[Category: Rna-binding]]
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[[Category: Rna-dependent rna-polymerase]]
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[[Category: Transmembrane]]
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[[Category: Viral protein]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Aug 19 13:20:42 2009''

Revision as of 10:20, 19 August 2009

Image:2wcx.jpg

Template:STRUCTURE 2wcx

CRYSTAL STRUCTURE OF HEPATITIS C VIRUS NS5B POLYMERASE IN COMPLEX WITH THIENOPYRROLE-BASED FINGER-LOOP INHIBITORS

About this Structure

2WCX is a 1 chain structure of sequence from Hepatitis c virus. Full crystallographic information is available from OCA.

Reference

  • Di Marco S, Volpari C, Tomei L, Altamura S, Harper S, Narjes F, Koch U, Rowley M, De Francesco R, Migliaccio G, Carfi A. Interdomain communication in hepatitis C virus polymerase abolished by small molecule inhibitors bound to a novel allosteric site. J Biol Chem. 2005 Aug 19;280(33):29765-70. Epub 2005 Jun 13. PMID:15955819 doi:http://dx.doi.org/10.1074/jbc.M505423200

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