3gfe
From Proteopedia
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| + | {{STRUCTURE_3gfe| PDB=3gfe | SCENE= }} | ||
| - | + | ===Crystal Structure of p38a Mitogen-Activated Protein Kinase in Complex with a Pyrazolopyridinone Inhibitor=== | |
| - | Description: Crystal Structure of p38a Mitogen-Activated Protein Kinase in Complex with a Pyrazolopyridinone Inhibitor | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed | + | <!-- |
| + | The line below this paragraph, {{ABSTRACT_PUBMED_19574047}}, adds the Publication Abstract to the page | ||
| + | (as it appears on PubMed at http://www.pubmed.gov), where 19574047 is the PubMed ID number. | ||
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| + | {{ABSTRACT_PUBMED_19574047}} | ||
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| + | ==About this Structure== | ||
| + | 3GFE is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GFE OCA]. | ||
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| + | ==Reference== | ||
| + | <ref group="xtra">PMID:19574047</ref><references group="xtra"/> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Mitogen-activated protein kinase]] | ||
| + | [[Category: Jordan, S.]] | ||
| + | [[Category: Mohr, C.]] | ||
| + | [[Category: Alternative splicing]] | ||
| + | [[Category: Atp-binding]] | ||
| + | [[Category: Cytoplasm]] | ||
| + | [[Category: Kinase]] | ||
| + | [[Category: Nucleotide-binding]] | ||
| + | [[Category: Nucleus]] | ||
| + | [[Category: Phosphoprotein]] | ||
| + | [[Category: Polymorphism]] | ||
| + | [[Category: Serine/threonine-protein kinase]] | ||
| + | [[Category: Transferase]] | ||
| + | |||
| + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jul 15 08:42:49 2009'' | ||
Revision as of 05:42, 15 July 2009
Crystal Structure of p38a Mitogen-Activated Protein Kinase in Complex with a Pyrazolopyridinone Inhibitor
Template:ABSTRACT PUBMED 19574047
About this Structure
3GFE is a 1 chain structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Wurz RP, Pettus LH, Xu S, Henkle B, Sherman L, Plant M, Miner K, McBride H, Wong LM, Saris CJ, Lee MR, Chmait S, Mohr C, Hsieh F, Tasker AS. Part 1: Structure-Activity Relationship (SAR) investigations of fused pyrazoles as potent, selective and orally available inhibitors of p38alpha mitogen-activated protein kinase. Bioorg Med Chem Lett. 2009 Aug 15;19(16):4724-8. Epub 2009 Jun 17. PMID:19574047 doi:10.1016/j.bmcl.2009.06.058
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