3cog
From Proteopedia
| Line 1: | Line 1: | ||
| - | {{Seed}} | ||
[[Image:3cog.png|left|200px]] | [[Image:3cog.png|left|200px]] | ||
| - | <!-- | ||
| - | The line below this paragraph, containing "STRUCTURE_3cog", creates the "Structure Box" on the page. | ||
| - | You may change the PDB parameter (which sets the PDB file loaded into the applet) | ||
| - | or the SCENE parameter (which sets the initial scene displayed when the page is loaded), | ||
| - | or leave the SCENE parameter empty for the default display. | ||
| - | --> | ||
{{STRUCTURE_3cog| PDB=3cog | SCENE= }} | {{STRUCTURE_3cog| PDB=3cog | SCENE= }} | ||
===Crystal structure of human cystathionase (Cystathionine gamma lyase) in complex with DL-propargylglycine=== | ===Crystal structure of human cystathionase (Cystathionine gamma lyase) in complex with DL-propargylglycine=== | ||
| - | |||
| - | <!-- | ||
| - | The line below this paragraph, {{ABSTRACT_PUBMED_19019829}}, adds the Publication Abstract to the page | ||
| - | (as it appears on PubMed at http://www.pubmed.gov), where 19019829 is the PubMed ID number. | ||
| - | --> | ||
{{ABSTRACT_PUBMED_19019829}} | {{ABSTRACT_PUBMED_19019829}} | ||
| - | |||
| - | ==Disease== | ||
| - | Known disease associated with this structure: Cystathioninuria OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=607657 607657]], Homocysteine, total plasma, elevated OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=607657 607657]] | ||
==About this Structure== | ==About this Structure== | ||
| - | + | [[3cog]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3COG OCA]. | |
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:019019829</ref><references group="xtra"/> |
[[Category: Cystathionine gamma-lyase]] | [[Category: Cystathionine gamma-lyase]] | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
| Line 60: | Line 45: | ||
[[Category: Welin, M.]] | [[Category: Welin, M.]] | ||
[[Category: Wikstrom, M.]] | [[Category: Wikstrom, M.]] | ||
| - | [[Category: Alternative splicing]] | ||
[[Category: Amino-acid biosynthesis]] | [[Category: Amino-acid biosynthesis]] | ||
[[Category: Cth]] | [[Category: Cth]] | ||
[[Category: Cysteine biosynthesis]] | [[Category: Cysteine biosynthesis]] | ||
| - | [[Category: Cytoplasm]] | ||
[[Category: Disease mutation]] | [[Category: Disease mutation]] | ||
[[Category: Inhibitor]] | [[Category: Inhibitor]] | ||
| Line 70: | Line 53: | ||
[[Category: Phosphoprotein]] | [[Category: Phosphoprotein]] | ||
[[Category: Plp]] | [[Category: Plp]] | ||
| - | [[Category: Polymorphism]] | ||
[[Category: Propargylglycine]] | [[Category: Propargylglycine]] | ||
[[Category: Pyridoxal phosphate]] | [[Category: Pyridoxal phosphate]] | ||
| Line 77: | Line 59: | ||
[[Category: Structural genomic]] | [[Category: Structural genomic]] | ||
[[Category: Structural genomics consortium]] | [[Category: Structural genomics consortium]] | ||
| - | |||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Apr 2 15:28:12 2009'' | ||
Revision as of 18:00, 7 January 2013
Crystal structure of human cystathionase (Cystathionine gamma lyase) in complex with DL-propargylglycine
Template:ABSTRACT PUBMED 19019829
About this Structure
3cog is a 4 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Sun Q, Collins R, Huang S, Holmberg-Schiavone L, Anand GS, Tan CH, van-den-Berg S, Deng LW, Moore PK, Karlberg T, Sivaraman J. Structural basis for the inhibition mechanism of human cystathionine gamma-lyase, an enzyme responsible for the production of H(2)S. J Biol Chem. 2009 Jan 30;284(5):3076-85. Epub 2008 Nov 19. PMID:19019829 doi:http://dx.doi.org/10.1074/jbc.M805459200
Categories: Cystathionine gamma-lyase | Homo sapiens | Arrowsmith, C H. | Berg, S Van den. | Berglund, H. | Busam, R D. | Collins, R. | Dahlgren, L G. | Edwards, A M. | Flodin, S. | Flores, A. | Graslund, S. | Hammarstrom, M. | Johansson, I. | Kallas, A. | Karlberg, T. | Kotenyova, T. | Lehtio, L. | Moche, M. | Nilsson, M E. | Nordlund, P. | Nyman, T. | Olesen, K. | Persson, C. | SGC, Structural Genomics Consortium. | Sagermark, J. | Schuler, H. | Svensson, L. | Thorsell, A G. | Tresaugues, L. | Weigelt, J. | Welin, M. | Wikstrom, M. | Amino-acid biosynthesis | Cth | Cysteine biosynthesis | Disease mutation | Inhibitor | Lyase | Phosphoprotein | Plp | Propargylglycine | Pyridoxal phosphate | Sgc | Sgc stockholm | Structural genomic | Structural genomics consortium
