3eww
From Proteopedia
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===D312N mutant of human orotidyl-5'-monophosphate decarboxylase in complex with 6-cyano-UMP, covalent adduct=== | ===D312N mutant of human orotidyl-5'-monophosphate decarboxylase in complex with 6-cyano-UMP, covalent adduct=== | ||
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==Disease== | ==Disease== | ||
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==About this Structure== | ==About this Structure== | ||
3EWW is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3EWW OCA]. | 3EWW is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3EWW OCA]. | ||
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| + | ==Reference== | ||
| + | <ref group="xtra">PMID:19472232</ref><references group="xtra"/> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Orotidine-5'-phosphate decarboxylase]] | [[Category: Orotidine-5'-phosphate decarboxylase]] | ||
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[[Category: Unusual catalysis]] | [[Category: Unusual catalysis]] | ||
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Revision as of 11:11, 16 December 2009
Contents |
D312N mutant of human orotidyl-5'-monophosphate decarboxylase in complex with 6-cyano-UMP, covalent adduct
Template:ABSTRACT PUBMED 19472232
Disease
Known disease associated with this structure: Oroticaciduria OMIM:[258900]
About this Structure
3EWW is a 2 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Heinrich D, Diederichsen U, Rudolph MG. Lys314 is a nucleophile in non-classical reactions of orotidine-5'-monophosphate decarboxylase. Chemistry. 2009 Jul 6;15(27):6619-25. PMID:19472232 doi:10.1002/chem.200900397
Page seeded by OCA on Wed Dec 16 13:11:40 2009
Categories: Homo sapiens | Orotidine-5'-phosphate decarboxylase | Diederichsen, U. | Heinrich, D. | Rudolph, M. | Wittmann, J. | Alternative splicing | Decarboxylase | Disease mutation | Glycosyltransferase | Lyase | Multifunctional enzyme | Polymorphism | Pyrimidine biosynthesis | Tim barrel | Transferase | Unusual catalysis
