2vap
From Proteopedia
(New page: 200px<br /> <applet load="2vap" size="450" color="white" frame="true" align="right" spinBox="true" caption="2vap, resolution 1.70Å" /> '''FTSZ GDP M. JANNASC...) |
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==About this Structure== | ==About this Structure== | ||
| - | 2VAP is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Methanocaldococcus_jannaschii Methanocaldococcus jannaschii]] with GDP as [[http://en.wikipedia.org/wiki/ligand ligand]]. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=2VAP OCA]]. | + | 2VAP is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Methanocaldococcus_jannaschii Methanocaldococcus jannaschii]] with GDP as [[http://en.wikipedia.org/wiki/ligand ligand]]. Structure known Active Site: AC1. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=2VAP OCA]]. |
==Reference== | ==Reference== | ||
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[[Category: tubulin homolog]] | [[Category: tubulin homolog]] | ||
| - | ''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Tue Oct 30 17:51:14 2007'' |
Revision as of 15:46, 30 October 2007
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FTSZ GDP M. JANNASCHII
Overview
FtsZ is a prokaryotic homologue of the eukaryotic cytoskeletal protein, tubulin and plays a central role in prokaryotic cell division. Both FtsZ, and tubulin are known to pass through cycles of polymerization and, depolymerization, but the structural mechanisms underlying this cycle, remain to be determined. Comparison of tubulin structures obtained in, different states has led to a model in which the tubulin monomer undergoes, a conformational switch between a "straight" form found in the walls of, microtubules and a "curved" form associated with depolymerization, and it, was proposed recently that this model may apply also to FtsZ. Here, we, present new structures of FtsZ from47 Aquifex aeolicus,47 Bacillus, subtilis, Methanococcus jannaschii and Pseudomonas aeruginosa that provide, ... [(full description)]
About this Structure
2VAP is a [Single protein] structure of sequence from [Methanocaldococcus jannaschii] with GDP as [ligand]. Structure known Active Site: AC1. Full crystallographic information is available from [OCA].
Reference
Structural Insights into the Conformational Variability of FtsZ., Oliva MA, Trambaiolo D, Lowe J, J Mol Biol. 2007 Nov 9;373(5):1229-42. Epub 2007 Aug 29. PMID:17900614
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