3h3c

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'''Unreleased structure'''
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{{Seed}}
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[[Image:3h3c.jpg|left|200px]]
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The entry 3h3c is ON HOLD
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{{STRUCTURE_3h3c| PDB=3h3c | SCENE= }}
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Authors: Han, S., Mistry, A.
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===Crystal structure of PYK2 in complex with Sulfoximine-substituted trifluoromethylpyrimidine analog===
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Description: Crystal structure of PYK2 in complex with Sulfoximine-substituted trifluoromethylpyrimidine analog
 
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed May 6 09:40:57 2009''
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{{ABSTRACT_PUBMED_19428251}}
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==About this Structure==
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3H3C is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3H3C OCA].
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==Reference==
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<ref group="xtra">PMID:19428251</ref><references group="xtra"/>
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[[Category: Homo sapiens]]
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[[Category: Non-specific protein-tyrosine kinase]]
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[[Category: Han, S.]]
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[[Category: Mistry, A.]]
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[[Category: Alternative splicing]]
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[[Category: Atp-binding]]
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[[Category: Cell membrane]]
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[[Category: Cytoplasm]]
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[[Category: Kinase]]
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[[Category: Membrane]]
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[[Category: Nucleotide-binding]]
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[[Category: Phosphoprotein]]
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[[Category: Polymorphism]]
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[[Category: Pyk2]]
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[[Category: Transferase]]
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[[Category: Tyrosine-protein kinase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed May 27 15:23:29 2009''

Revision as of 12:23, 27 May 2009

Image:3h3c.jpg

Template:STRUCTURE 3h3c

Crystal structure of PYK2 in complex with Sulfoximine-substituted trifluoromethylpyrimidine analog

Template:ABSTRACT PUBMED 19428251

About this Structure

3H3C is a 1 chain structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Walker DP, Zawistoski MP, McGlynn MA, Li JC, Kung DW, Bonnette PC, Baumann A, Buckbinder L, Houser JA, Boer J, Mistry A, Han S, Xing L, Guzman-Perez A. Sulfoximine-substituted trifluoromethylpyrimidine analogs as inhibitors of proline-rich tyrosine kinase 2 (PYK2) show reduced hERG activity. Bioorg Med Chem Lett. 2009 Jun 15;19(12):3253-8. Epub 2009 Apr 24. PMID:19428251 doi:10.1016/j.bmcl.2009.04.093

Page seeded by OCA on Wed May 27 15:23:29 2009

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