3h6w

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'''Unreleased structure'''
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{{Seed}}
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[[Image:3h6w.png|left|200px]]
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The entry 3h6w is ON HOLD until Paper Publication
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{{STRUCTURE_3h6w| PDB=3h6w | SCENE= }}
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Authors: Hald, H., Gajhede, M., Kastrup, J.S.
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===Crystal structure of the iGluR2 ligand-binding core (S1S2J-N754S) in complex with glutamate and NS5217 at 1.50 A resolution===
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Description: Crystal structure of the iGluR2 ligand-binding core (S1S2J-N754S) in complex with glutamate and NS5217 at 1.50 A resolution
 
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed May 13 09:35:41 2009''
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{{ABSTRACT_PUBMED_19591837}}
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==About this Structure==
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3H6W is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3H6W OCA].
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==Reference==
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<ref group="xtra">PMID:19591837</ref><ref group="xtra">PMID:11086992</ref><ref group="xtra">PMID:12015593</ref><references group="xtra"/>
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[[Category: Rattus norvegicus]]
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[[Category: Gajhede, M.]]
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[[Category: Hald, H.]]
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[[Category: Kastrup, J S.]]
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[[Category: Allosteric modulation]]
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[[Category: Ampa receptor ligand-binding core]]
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[[Category: Iglur2 s1s2j-n754]]
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[[Category: Membrane protein]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Sep 9 08:51:16 2009''

Revision as of 05:51, 9 September 2009

Image:3h6w.png

Template:STRUCTURE 3h6w

Crystal structure of the iGluR2 ligand-binding core (S1S2J-N754S) in complex with glutamate and NS5217 at 1.50 A resolution

Template:ABSTRACT PUBMED 19591837

About this Structure

3H6W is a 2 chains structure of sequences from Rattus norvegicus. Full crystallographic information is available from OCA.

Reference

  • Hald H, Ahring PK, Timmermann DB, Liljefors T, Gajhede M, Kastrup JS. Distinct structural features of cyclothiazide are responsible for effects on peak current amplitude and desensitization kinetics at iGluR2. J Mol Biol. 2009 Sep 4;391(5):906-17. Epub 2009 Jul 8. PMID:19591837 doi:10.1016/j.jmb.2009.07.002
  • Armstrong N, Gouaux E. Mechanisms for activation and antagonism of an AMPA-sensitive glutamate receptor: crystal structures of the GluR2 ligand binding core. Neuron. 2000 Oct;28(1):165-81. PMID:11086992
  • Sun Y, Olson R, Horning M, Armstrong N, Mayer M, Gouaux E. Mechanism of glutamate receptor desensitization. Nature. 2002 May 16;417(6886):245-53. PMID:12015593 doi:10.1038/417245a

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