3orc

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[[Image:3orc.png|left|200px]]
 
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{{STRUCTURE_3orc| PDB=3orc | SCENE= }}
{{STRUCTURE_3orc| PDB=3orc | SCENE= }}
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===CRYSTAL STRUCTURE OF AN ENGINEERED CRO MONOMER BOUND NONSPECIFICALLY TO DNA===
===CRYSTAL STRUCTURE OF AN ENGINEERED CRO MONOMER BOUND NONSPECIFICALLY TO DNA===
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{{ABSTRACT_PUBMED_9684880}}
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==Function==
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[[http://www.uniprot.org/uniprot/RCRO_LAMBD RCRO_LAMBD]] Cro represses genes normally expressed in early phage development and is necessary for the late stage of lytic growth. It does this by binding to the OL and OR operators regions normally used by the repressor protein for lysogenic maintenance.
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{{ABSTRACT_PUBMED_9684880}}
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==About this Structure==
==About this Structure==
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3ORC is a 3 chains structure of sequences from [http://en.wikipedia.org/wiki/Enterobacteria_phage_lambda Enterobacteria phage lambda]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ORC OCA].
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[[3orc]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Enterobacteria_phage_lambda Enterobacteria phage lambda]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ORC OCA].
==Reference==
==Reference==
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<ref group="xtra">PMID:9684880</ref><references group="xtra"/>
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<ref group="xtra">PMID:009684880</ref><references group="xtra"/><references/>
[[Category: Enterobacteria phage lambda]]
[[Category: Enterobacteria phage lambda]]
[[Category: Albright, R A.]]
[[Category: Albright, R A.]]
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[[Category: Bacteriophage lambda]]
[[Category: Bacteriophage lambda]]
[[Category: Cro]]
[[Category: Cro]]
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[[Category: Gene regulation/dna complex]]
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[[Category: Gene regulation-dna complex]]
[[Category: Helix-turn-helix]]
[[Category: Helix-turn-helix]]
[[Category: Monomer-dimer]]
[[Category: Monomer-dimer]]
[[Category: Protein-dna interaction]]
[[Category: Protein-dna interaction]]
[[Category: Repressor]]
[[Category: Repressor]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed May 20 15:09:52 2009''
 

Revision as of 08:26, 2 May 2013

Template:STRUCTURE 3orc

Contents

CRYSTAL STRUCTURE OF AN ENGINEERED CRO MONOMER BOUND NONSPECIFICALLY TO DNA

Template:ABSTRACT PUBMED 9684880

Function

[RCRO_LAMBD] Cro represses genes normally expressed in early phage development and is necessary for the late stage of lytic growth. It does this by binding to the OL and OR operators regions normally used by the repressor protein for lysogenic maintenance.

About this Structure

3orc is a 3 chain structure with sequence from Enterobacteria phage lambda. Full crystallographic information is available from OCA.

Reference

  • Albright RA, Mossing MC, Matthews BW. Crystal structure of an engineered Cro monomer bound nonspecifically to DNA: possible implications for nonspecific binding by the wild-type protein. Protein Sci. 1998 Jul;7(7):1485-94. PMID:9684880

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