3h63

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'''Unreleased structure'''
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{{Seed}}
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[[Image:3h63.jpg|left|200px]]
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The entry 3h63 is ON HOLD until Paper Publication
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{{STRUCTURE_3h63| PDB=3h63 | SCENE= }}
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Authors: Bertini, I., Calderone, V., Fragai, M., Luchinat, C., Talluri, E.
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===Catalytic domain of human Serine/Threonine Phosphatase 5 (PP5c) with two Mn2+ atoms originally soaked with cantharidin (which is present in the structure in the hydrolyzed form)===
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Description:
 
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed May 20 16:37:56 2009''
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(as it appears on PubMed at http://www.pubmed.gov), where 19601647 is the PubMed ID number.
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{{ABSTRACT_PUBMED_19601647}}
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==About this Structure==
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3H63 is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3H63 OCA].
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==Reference==
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<ref group="xtra">PMID:19601647</ref><references group="xtra"/>
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[[Category: Homo sapiens]]
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[[Category: Phosphoprotein phosphatase]]
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[[Category: Bertini, I.]]
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[[Category: Calderone, V.]]
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[[Category: Fragai, M.]]
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[[Category: Luchinat, C.]]
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[[Category: Talluri, E.]]
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[[Category: Cytoplasm]]
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[[Category: Drug design]]
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[[Category: Hydrolase]]
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[[Category: Inhibitor]]
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[[Category: Iron]]
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[[Category: Manganese]]
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[[Category: Metal-binding]]
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[[Category: Metalloenzyme]]
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[[Category: Nucleus]]
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[[Category: Phosphatase]]
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[[Category: Protein phosphatase]]
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[[Category: Tpr repeat]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Sep 30 09:18:23 2009''

Revision as of 07:18, 30 September 2009

Template:STRUCTURE 3h63

Catalytic domain of human Serine/Threonine Phosphatase 5 (PP5c) with two Mn2+ atoms originally soaked with cantharidin (which is present in the structure in the hydrolyzed form)

Template:ABSTRACT PUBMED 19601647

About this Structure

3H63 is a 2 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Bertini I, Calderone V, Fragai M, Luchinat C, Talluri E. Structural basis of serine/threonine phosphatase inhibition by the archetypal small molecules cantharidin and norcantharidin. J Med Chem. 2009 Aug 13;52(15):4838-43. PMID:19601647 doi:10.1021/jm900610k

Page seeded by OCA on Wed Sep 30 09:18:23 2009

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