3hc8

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'''Unreleased structure'''
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{{Seed}}
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[[Image:3hc8.jpg|left|200px]]
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The entry 3hc8 is ON HOLD
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{{STRUCTURE_3hc8| PDB=3hc8 | SCENE= }}
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Authors: Hughes, R.O., Stallings, W.C, Cubbage, J.W., Williams, J.M.
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===Investigation of Aminopyridiopyrazinones as PDE5 Inhibitors: Evaluation of Modifications to the Central Ring System.===
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Description: Investigation of Aminopyridiopyrazinones as PDE5 Inhibitors: Evaluation of Modifications to the Central Ring System.
 
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed May 20 16:39:15 2009''
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{{ABSTRACT_PUBMED_19539468}}
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==About this Structure==
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3HC8 is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HC8 OCA].
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==Reference==
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<ref group="xtra">PMID:19539468</ref><references group="xtra"/>
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[[Category: Homo sapiens]]
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[[Category: Cubbage, J W.]]
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[[Category: Hughes, R O.]]
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[[Category: Stallings, W C]]
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[[Category: Williams, J M.]]
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[[Category: Alternative splicing]]
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[[Category: Camp]]
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[[Category: Cgmp]]
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[[Category: Cgmp-binding]]
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[[Category: Hydrolase]]
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[[Category: Inhibition]]
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[[Category: Magnesium]]
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[[Category: Metal-binding]]
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[[Category: Nucleotide-binding]]
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[[Category: Pde-5]]
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[[Category: Pde5]]
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[[Category: Phosphoprotein]]
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[[Category: Polymorphism allosteric enzyme]]
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[[Category: Zinc]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jul 8 09:26:01 2009''

Revision as of 06:26, 8 July 2009

Image:3hc8.jpg

Template:STRUCTURE 3hc8

Investigation of Aminopyridiopyrazinones as PDE5 Inhibitors: Evaluation of Modifications to the Central Ring System.

Template:ABSTRACT PUBMED 19539468

About this Structure

3HC8 is a 1 chain structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Hughes RO, Walker JK, Cubbage JW, Fobian YM, Rogier DJ, Heasley SE, Blevis-Bal RM, Benson AG, Owen DR, Jacobsen EJ, Freskos JN, Molyneaux JM, Brown DL, Stallings WC, Acker BA, Maddux TM, Tollefson MB, Williams JM, Moon JB, Mischke BV, Rumsey JM, Zheng Y, Macinnes A, Bond BR, Yu Y. Investigation of aminopyridiopyrazinones as PDE5 inhibitors: Evaluation of modifications to the central ring system. Bioorg Med Chem Lett. 2009 Aug 1;19(15):4092-6. Epub 2009 Jun 6. PMID:19539468 doi:10.1016/j.bmcl.2009.06.004

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