3gxt

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Revision as of 06:13, 17 June 2009

Image:3gxt.png

Template:STRUCTURE 3gxt

Contents

Crystal structure of alpha-galactosidase A at pH 4.5 complexed with 1-deoxygalactonijirimycin

Template:ABSTRACT PUBMED 19374450

Disease

Known disease associated with this structure: Fabry disease OMIM:[300644], Fabry disease, cardiac variant OMIM:[300644]

About this Structure

3GXT is a 2 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Lieberman RL, D'aquino JA, Ringe D, Petsko GA. Effects of pH and Iminosugar Pharmacological Chaperones on Lysosomal Glycosidase Structure and Stability. Biochemistry. 2009 May 1. PMID:19374450 doi:http://dx.doi.org/10.1021/bi9002265

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