3g42
From Proteopedia
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===Crystal Structure of TACE with Tryptophan Sulfonamide Derivative Inhibitor=== | ===Crystal Structure of TACE with Tryptophan Sulfonamide Derivative Inhibitor=== | ||
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==About this Structure== | ==About this Structure== | ||
| - | + | [[3g42]] is a 4 chain structure of [[A Disintegrin And Metalloproteinase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3G42 OCA]. | |
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| + | ==See Also== | ||
| + | *[[A Disintegrin And Metalloproteinase|A Disintegrin And Metalloproteinase]] | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:019410464</ref><references group="xtra"/> |
[[Category: ADAM 17 endopeptidase]] | [[Category: ADAM 17 endopeptidase]] | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
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[[Category: Xu, W.]] | [[Category: Xu, W.]] | ||
[[Category: Zhang, Y H.]] | [[Category: Zhang, Y H.]] | ||
| - | [[Category: Alternative splicing]] | ||
[[Category: Cleavage on pair of basic residue]] | [[Category: Cleavage on pair of basic residue]] | ||
[[Category: Glycoprotein]] | [[Category: Glycoprotein]] | ||
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[[Category: Notch signaling pathway]] | [[Category: Notch signaling pathway]] | ||
[[Category: Phosphoprotein]] | [[Category: Phosphoprotein]] | ||
| - | [[Category: Polymorphism]] | ||
[[Category: Protease]] | [[Category: Protease]] | ||
[[Category: Sh3-binding]] | [[Category: Sh3-binding]] | ||
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[[Category: Tace/adam-17]] | [[Category: Tace/adam-17]] | ||
[[Category: Transmembrane]] | [[Category: Transmembrane]] | ||
| - | [[Category: Zinc]] | ||
[[Category: Zn-endopeptidase]] | [[Category: Zn-endopeptidase]] | ||
[[Category: Zymogen]] | [[Category: Zymogen]] | ||
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Revision as of 19:08, 26 July 2012
Contents |
Crystal Structure of TACE with Tryptophan Sulfonamide Derivative Inhibitor
Template:ABSTRACT PUBMED 19410464
About this Structure
3g42 is a 4 chain structure of A Disintegrin And Metalloproteinase with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Park K, Gopalsamy A, Aplasca A, Ellingboe JW, Xu W, Zhang Y, Levin JI. Synthesis and activity of tryptophan sulfonamide derivatives as novel non-hydroxamate TNF-alpha converting enzyme (TACE) inhibitors. Bioorg Med Chem. 2009 Jun 1;17(11):3857-65. Epub 2009 Apr 22. PMID:19410464 doi:10.1016/j.bmc.2009.04.033
Categories: ADAM 17 endopeptidase | Homo sapiens | Aplasca, A. | Gopalsamy, A. | K., Park. | Levin, J I. | Xu, W. | Zhang, Y H. | Cleavage on pair of basic residue | Glycoprotein | Hydrolase | Membrane | Metal-binding | Metalloprotease | Notch signaling pathway | Phosphoprotein | Protease | Sh3-binding | Tace-inhibitor complex | Tace/adam-17 | Transmembrane | Zn-endopeptidase | Zymogen
