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3hhm

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'''Unreleased structure'''
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{{Seed}}
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[[Image:3hhm.jpg|left|200px]]
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The entry 3hhm is ON HOLD until Paper Publication
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{{STRUCTURE_3hhm| PDB=3hhm | SCENE= }}
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Authors: Amzel, L.M., Vogelstein, B., Gabelli, S.B., Mandelker, D.
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===Crystal structure of p110alpha H1047R mutant in complex with niSH2 of p85alpha and the drug wortmannin===
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Description: Crystal structure of p110alpha H1047R mutant in complex with niSH2 of p85alpha and the drug wortmannin
 
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jun 10 17:59:06 2009''
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==Disease==
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Known disease associated with this structure: Breast cancer, somatic OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=171834 171834]], Colorectal cancer, somatic OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=171834 171834]], Gastric cancer, somatic OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=171834 171834]], Hepatocellular carcinoma, somatic OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=171834 171834]], Keratosis, seborrheic, somatic OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=171834 171834]], Nevus, epidermal OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=171834 171834]], Nonsmall cell lung cancer, somatic OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=171834 171834]], Ovarian cancer, somatic OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=171834 171834]]
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==About this Structure==
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3HHM is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HHM OCA].
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[[Category: Homo sapiens]]
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[[Category: Phosphatidylinositol-4,5-bisphosphate 3-kinase]]
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[[Category: Amzel, L M.]]
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[[Category: Gabelli, S B.]]
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[[Category: Mandelker, D.]]
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[[Category: Vogelstein, B.]]
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[[Category: 5-triphosphate]]
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[[Category: Atp-binding]]
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[[Category: Disease mutation]]
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[[Category: H1047r]]
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[[Category: Kinase]]
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[[Category: Nucleotide-binding]]
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[[Category: Oncogene]]
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[[Category: P110]]
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[[Category: P85]]
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[[Category: Phosphatidilynositol 3]]
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[[Category: Pi3k]]
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[[Category: Pi3kca]]
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[[Category: Pik3r1]]
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[[Category: Polymorphism]]
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[[Category: Transferase]]
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[[Category: Transferase/oncoprotein complex]]
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[[Category: Wortmannin]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Sep 30 09:28:29 2009''

Revision as of 07:28, 30 September 2009

Image:3hhm.jpg

Template:STRUCTURE 3hhm

Crystal structure of p110alpha H1047R mutant in complex with niSH2 of p85alpha and the drug wortmannin

Disease

Known disease associated with this structure: Breast cancer, somatic OMIM:[171834], Colorectal cancer, somatic OMIM:[171834], Gastric cancer, somatic OMIM:[171834], Hepatocellular carcinoma, somatic OMIM:[171834], Keratosis, seborrheic, somatic OMIM:[171834], Nevus, epidermal OMIM:[171834], Nonsmall cell lung cancer, somatic OMIM:[171834], Ovarian cancer, somatic OMIM:[171834]

About this Structure

3HHM is a 2 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Page seeded by OCA on Wed Sep 30 09:28:29 2009

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OCA

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