3g0u

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[[Image:3g0u.png|left|200px]]
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{{STRUCTURE_3g0u| PDB=3g0u | SCENE= }}
{{STRUCTURE_3g0u| PDB=3g0u | SCENE= }}
===Human dihydroorotate dehydrogenase in complex with a leflunomide derivative inhibitor 4===
===Human dihydroorotate dehydrogenase in complex with a leflunomide derivative inhibitor 4===
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{{ABSTRACT_PUBMED_19351152}}
{{ABSTRACT_PUBMED_19351152}}
==About this Structure==
==About this Structure==
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3G0U is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3G0U OCA].
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[[3g0u]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3G0U OCA].
==Reference==
==Reference==
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<ref group="xtra">PMID:19351152</ref><references group="xtra"/>
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<ref group="xtra">PMID:019351152</ref><references group="xtra"/>
[[Category: Dihydroorotate oxidase]]
[[Category: Dihydroorotate oxidase]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Mitochondrion inner membrane]]
[[Category: Mitochondrion inner membrane]]
[[Category: Oxidoreductase]]
[[Category: Oxidoreductase]]
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[[Category: Polymorphism]]
 
[[Category: Pyrimidine biosynthesis]]
[[Category: Pyrimidine biosynthesis]]
[[Category: Tim-barrel]]
[[Category: Tim-barrel]]
[[Category: Transit peptide]]
[[Category: Transit peptide]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jun 10 18:03:23 2009''
 

Revision as of 14:50, 20 February 2013

Template:STRUCTURE 3g0u

Human dihydroorotate dehydrogenase in complex with a leflunomide derivative inhibitor 4

Template:ABSTRACT PUBMED 19351152

About this Structure

3g0u is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Davies M, Heikkila T, McConkey GA, Fishwick CW, Parsons MR, Johnson AP. Structure-based design, synthesis, and characterization of inhibitors of human and Plasmodium falciparum dihydroorotate dehydrogenases. J Med Chem. 2009 May 14;52(9):2683-93. PMID:19351152 doi:10.1021/jm800963t

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