1e50
From Proteopedia
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[[Image:1e50.png|left|200px]] | [[Image:1e50.png|left|200px]] | ||
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{{STRUCTURE_1e50| PDB=1e50 | SCENE= }} | {{STRUCTURE_1e50| PDB=1e50 | SCENE= }} | ||
===AML1/CBF COMPLEX=== | ===AML1/CBF COMPLEX=== | ||
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{{ABSTRACT_PUBMED_10856244}} | {{ABSTRACT_PUBMED_10856244}} | ||
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| - | ==Disease== | ||
| - | Known disease associated with this structure: Leukemia, acute myeloid OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=151385 151385]], Platelet disorder, familial, with associated myeloid malignancy OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=151385 151385]], Rheumatoid arthritis, susceptibility to OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=151385 151385]], Myeloid leukemia, acute, M4Eo subtype OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=121360 121360]] | ||
==About this Structure== | ==About this Structure== | ||
| - | + | [[1e50]] is a 10 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1E50 OCA]. | |
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:010856244</ref><references group="xtra"/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Bravo, J.]] | [[Category: Bravo, J.]] | ||
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[[Category: Warren, A J.]] | [[Category: Warren, A J.]] | ||
[[Category: Williams, R L.]] | [[Category: Williams, R L.]] | ||
| + | [[Category: Transcription]] | ||
[[Category: Transcription factor]] | [[Category: Transcription factor]] | ||
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| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jun 10 22:09:15 2009'' | ||
Revision as of 09:59, 31 October 2012
AML1/CBF COMPLEX
Template:ABSTRACT PUBMED 10856244
About this Structure
1e50 is a 10 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Warren AJ, Bravo J, Williams RL, Rabbitts TH. Structural basis for the heterodimeric interaction between the acute leukaemia-associated transcription factors AML1 and CBFbeta. EMBO J. 2000 Jun 15;19(12):3004-15. PMID:10856244 doi:10.1093/emboj/19.12.3004
