3fxi
From Proteopedia
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[[Image:3fxi.png|left|200px]] | [[Image:3fxi.png|left|200px]] | ||
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{{ABSTRACT_PUBMED_19252480}} | {{ABSTRACT_PUBMED_19252480}} | ||
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| - | ==Disease== | ||
| - | Known disease associated with this structure: Endotoxin hyporesponsiveness OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=603030 603030]], Colorectal cancer, susceptibility to OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=603030 603030]], Longevity, susceptibility to OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=603030 603030]], Macular degeneration, age-related, 10 OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=603030 603030]] | ||
==About this Structure== | ==About this Structure== | ||
| - | + | [[3fxi]] is a 4 chain structure of [[Toll-like Receptors]] with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli] and [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. The November 2011 RCSB PDB [http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''Toll-like Receptors'' by David Goodsell is [http://dx.doi.org/10.2210/rcsb_pdb/mom_2011_11 10.2210/rcsb_pdb/mom_2011_11]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FXI OCA]. | |
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| + | ==See Also== | ||
| + | *[[Toll-like Receptors|Toll-like Receptors]] | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:019252480</ref><ref group="xtra">PMID:020485341</ref><references group="xtra"/> |
[[Category: Escherichia coli]] | [[Category: Escherichia coli]] | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
| + | [[Category: RCSB PDB Molecule of the Month]] | ||
| + | [[Category: Toll-like Receptors]] | ||
[[Category: Kim, H M.]] | [[Category: Kim, H M.]] | ||
[[Category: Lee, J O.]] | [[Category: Lee, J O.]] | ||
[[Category: Park, B S.]] | [[Category: Park, B S.]] | ||
[[Category: Song, D H.]] | [[Category: Song, D H.]] | ||
| - | [[Category: Alternative splicing]] | ||
[[Category: Glycoprotein]] | [[Category: Glycoprotein]] | ||
[[Category: Immune response]] | [[Category: Immune response]] | ||
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[[Category: Leucine rich repeat]] | [[Category: Leucine rich repeat]] | ||
[[Category: Membrane]] | [[Category: Membrane]] | ||
| - | [[Category: Polymorphism]] | ||
[[Category: Receptor]] | [[Category: Receptor]] | ||
[[Category: Secreted]] | [[Category: Secreted]] | ||
[[Category: Transmembrane]] | [[Category: Transmembrane]] | ||
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| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jun 10 22:12:40 2009'' | ||
Revision as of 06:51, 20 June 2012
Contents |
Crystal structure of the human TLR4-human MD-2-E.coli LPS Ra complex
Template:ABSTRACT PUBMED 19252480
About this Structure
3fxi is a 4 chain structure of Toll-like Receptors with sequence from Escherichia coli and Homo sapiens. The November 2011 RCSB PDB Molecule of the Month feature on Toll-like Receptors by David Goodsell is 10.2210/rcsb_pdb/mom_2011_11. Full crystallographic information is available from OCA.
See Also
Reference
- Park BS, Song DH, Kim HM, Choi BS, Lee H, Lee JO. The structural basis of lipopolysaccharide recognition by the TLR4-MD-2 complex. Nature. 2009 Apr 30;458(7242):1191-5. Epub 2009 Mar 1. PMID:19252480 doi:10.1038/nature07830
- Lin SC, Lo YC, Wu H. Helical assembly in the MyD88-IRAK4-IRAK2 complex in TLR/IL-1R signalling. Nature. 2010 Jun 17;465(7300):885-90. Epub 2010 May 19. PMID:20485341 doi:10.1038/nature09121
Categories: Escherichia coli | Homo sapiens | RCSB PDB Molecule of the Month | Toll-like Receptors | Kim, H M. | Lee, J O. | Park, B S. | Song, D H. | Glycoprotein | Immune response | Immune system | Inflammatory response | Innate immunity | Leucine rich repeat | Membrane | Receptor | Secreted | Transmembrane
