3gol

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Revision as of 05:29, 25 June 2009

Template:STRUCTURE 3gol

HCV NS5b polymerase in complex with 1,5 benzodiazepine inhibitor (R)-11d

Template:ABSTRACT PUBMED 19342234

About this Structure

3GOL is a 2 chains structure of sequences from Viruses. Full crystallographic information is available from OCA.

Reference

  • McGowan D, Nyanguile O, Cummings MD, Vendeville S, Vandyck K, Van den Broeck W, Boutton CW, De Bondt H, Quirynen L, Amssoms K, Bonfanti JF, Last S, Rombauts K, Tahri A, Hu L, Delouvroy F, Vermeiren K, Vandercruyssen G, Van der Helm L, Cleiren E, Mostmans W, Lory P, Pille G, Van Emelen K, Fanning G, Pauwels F, Lin TI, Simmen K, Raboisson P. 1,5-Benzodiazepine inhibitors of HCV NS5B polymerase. Bioorg Med Chem Lett. 2009 May 1;19(9):2492-6. Epub 2009 Mar 14. PMID:19342234 doi:10.1016/j.bmcl.2009.03.035

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