User:Tilman Schirmer/Sandbox 201
From Proteopedia
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<scene name='User:Tilman_Schirmer/Sandbox_201/Protomer/5'>PleD</scene> from ''Caulobacter crescentus'' is a response regulator with an unorthodox catalytic, diguanylate cyclase, output domain. It is composed of a canonical CheY-like response regulator receiver (<scene name='User:Tilman_Schirmer/Sandbox_201/Protomer/7'>Rec</scene>) domain, | <scene name='User:Tilman_Schirmer/Sandbox_201/Protomer/5'>PleD</scene> from ''Caulobacter crescentus'' is a response regulator with an unorthodox catalytic, diguanylate cyclase, output domain. It is composed of a canonical CheY-like response regulator receiver (<scene name='User:Tilman_Schirmer/Sandbox_201/Protomer/7'>Rec</scene>) domain, | ||
| - | a Rec-like (scene name='User:Tilman_Schirmer/Sandbox_201/Protomer_rec_prime/2'>Rec'</scene>) adaptor domain, | + | a Rec-like (<scene name='User:Tilman_Schirmer/Sandbox_201/Protomer_rec_prime/2'>Rec'</scene>) adaptor domain, |
and a C-terminal <scene name='User:Tilman_Schirmer/Sandbox_201/Protomer_ggdef/1'>GGDEF</scene> domain that confers the catalytic acitvity. | and a C-terminal <scene name='User:Tilman_Schirmer/Sandbox_201/Protomer_ggdef/1'>GGDEF</scene> domain that confers the catalytic acitvity. | ||
Revision as of 20:05, 20 June 2009
PleD
Contents |
Intro
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from Caulobacter crescentus is a response regulator with an unorthodox catalytic, diguanylate cyclase, output domain. It is composed of a canonical CheY-like response regulator receiver () domain,
a Rec-like () adaptor domain,
and a C-terminal domain that confers the catalytic acitvity.
Substrate binding site
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Allosteric product binding site
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C-di-GMP
Primary inhibition site (Ip)
Secondary inhibition site (Is)
Primary and secondary inhibition sites
Two conformations
non-activated (1w25)
activated (BeF3- modified; 2v0n)
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Non-activated conformation
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: , ,
Activated conformation
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