User:Tilman Schirmer/Sandbox 200
From Proteopedia
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====[[User:Tilman Schirmer/Sandbox 212|PleD activation]]==== | ====[[User:Tilman Schirmer/Sandbox 212|PleD activation]]==== | ||
====[[User:Tilman Schirmer/Sandbox 213|PleD allosteric product inhibition]]==== | ====[[User:Tilman Schirmer/Sandbox 213|PleD allosteric product inhibition]]==== | ||
| + | ===[[User:Tilman Schirmer/Sandbox 204|WspR]]=== | ||
== [[User:Tilman Schirmer/Sandbox 202|C-di-GMP specific phosphodiesterases]] == | == [[User:Tilman Schirmer/Sandbox 202|C-di-GMP specific phosphodiesterases]] == | ||
Revision as of 20:39, 30 June 2009
Cyclic di-GMP signaling
Contents |
Intro
Diguanylate cyclases
The condensation reaction 2 GTP -> c-di-GMP + 2 PPi is catalyzed by GGDEF domains that typically occur in combination with sensory or regulator domains. The structures of two diguanylate cyclases (PleD and WspR) have been determined, both being response regulators with a response regulator receiver (Rec) and a GGDEF output (effector) domain. Response regulators are activated through phosphorylation of a conserved aspartate by cognate histidine kinases.
