This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
3fub
From Proteopedia
| Line 1: | Line 1: | ||
| - | {{Seed}} | ||
[[Image:3fub.png|left|200px]] | [[Image:3fub.png|left|200px]] | ||
| - | <!-- | ||
| - | The line below this paragraph, containing "STRUCTURE_3fub", creates the "Structure Box" on the page. | ||
| - | You may change the PDB parameter (which sets the PDB file loaded into the applet) | ||
| - | or the SCENE parameter (which sets the initial scene displayed when the page is loaded), | ||
| - | or leave the SCENE parameter empty for the default display. | ||
| - | --> | ||
{{STRUCTURE_3fub| PDB=3fub | SCENE= }} | {{STRUCTURE_3fub| PDB=3fub | SCENE= }} | ||
===Crystal structure of GDNF-GFRalpha1 complex=== | ===Crystal structure of GDNF-GFRalpha1 complex=== | ||
| - | |||
| - | <!-- | ||
| - | The line below this paragraph, {{ABSTRACT_PUBMED_19478429}}, adds the Publication Abstract to the page | ||
| - | (as it appears on PubMed at http://www.pubmed.gov), where 19478429 is the PubMed ID number. | ||
| - | --> | ||
{{ABSTRACT_PUBMED_19478429}} | {{ABSTRACT_PUBMED_19478429}} | ||
| - | |||
| - | ==Disease== | ||
| - | Known disease associated with this structure: Central hypoventilation syndrome OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=600837 600837]], Hirschsprung disease OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=600837 600837]], Pheochromocytoma, modifier of OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=600837 600837]] | ||
==About this Structure== | ==About this Structure== | ||
| - | + | [[3fub]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FUB OCA]. | |
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:019478429</ref><references group="xtra"/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Rattus norvegicus]] | [[Category: Rattus norvegicus]] | ||
| Line 32: | Line 17: | ||
[[Category: V., Parkash.]] | [[Category: V., Parkash.]] | ||
[[Category: All alpha gdnf]] | [[Category: All alpha gdnf]] | ||
| - | [[Category: Alternative splicing]] | ||
[[Category: Cell membrane]] | [[Category: Cell membrane]] | ||
[[Category: Cleavage on pair of basic residue]] | [[Category: Cleavage on pair of basic residue]] | ||
| Line 45: | Line 29: | ||
[[Category: Lipoprotein]] | [[Category: Lipoprotein]] | ||
[[Category: Membrane]] | [[Category: Membrane]] | ||
| - | [[Category: Polymorphism]] | ||
[[Category: Receptor]] | [[Category: Receptor]] | ||
[[Category: Secreted]] | [[Category: Secreted]] | ||
| - | |||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat Jul 4 18:03:13 2009'' | ||
Revision as of 14:35, 20 February 2013
Crystal structure of GDNF-GFRalpha1 complex
Template:ABSTRACT PUBMED 19478429
About this Structure
3fub is a 4 chain structure with sequence from Homo sapiens and Rattus norvegicus. Full crystallographic information is available from OCA.
Reference
- Parkash V, Goldman A. Comparison of GFL-GFRalpha complexes: further evidence relating GFL bend angle to RET signalling. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2009 Jun 1;65(Pt, 6):551-8. Epub 2009 May 23. PMID:19478429 doi:10.1107/S1744309109017722
Categories: Homo sapiens | Rattus norvegicus | A., Goldman. | V., Parkash. | All alpha gdnf | Cell membrane | Cleavage on pair of basic residue | Cystine knot | Disease mutation | Gfralpha1 | Glycoprotein | Gpi-anchor | Growth factor | Hirschsprung disease | Hormone | Lipoprotein | Membrane | Receptor | Secreted
