This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
C-di-GMP
From Proteopedia
| Line 3: | Line 3: | ||
[http://www.uniprot.org/keywords/973 UNIPROT link] | [http://www.uniprot.org/keywords/973 UNIPROT link] | ||
| - | <applet load='2v0n' scene='C-di-GMP/C-di-gmp/1' size='400' frame='true' align='right' caption='cyclic di-GMP' /> | + | <applet load='2v0n' scene='C-di-GMP/C-di-gmp/1' size='400' frame='true' align='right' caption='cyclic di-GMP [[2v0n]]' /> |
C-di-GMP is a second messenger that mediates the regulation of cell-surface associated traits in bacteria. | C-di-GMP is a second messenger that mediates the regulation of cell-surface associated traits in bacteria. | ||
| Line 14: | Line 14: | ||
<br><br><br><br><br><br><br><br><br><br><br><br><br><br> | <br><br><br><br><br><br><br><br><br><br><br><br><br><br> | ||
| + | |||
| + | ==References== | ||
| + | Reviews: | ||
| + | <ref group="xtra">PMID:19287449</ref><ref group="xtra">PMID:16895465</ref> | ||
| + | <references group="xtra"/> | ||
Revision as of 10:08, 15 July 2009
Cyclic di-GMP, (bis-(3'-5') cyclic diguanylic acid)
|
C-di-GMP is a second messenger that mediates the regulation of cell-surface associated traits in bacteria.
is a cyclic dinucleotide with a 12-membered macro-cycle composed of the the phosphate and ribose moieties. It tends to associate to form with intercalated, stacked bases.
Several protein structures involved in c-di-GMP signaling have been determined (reviewed in User:Tilman_Schirmer/Sandbox_200).
References
Reviews:
- Hengge R. Principles of c-di-GMP signalling in bacteria. Nat Rev Microbiol. 2009 Apr;7(4):263-73. PMID:19287449 doi:10.1038/nrmicro2109
- Jenal U, Malone J. Mechanisms of cyclic-di-GMP signaling in bacteria. Annu Rev Genet. 2006;40:385-407. PMID:16895465 doi:10.1146/annurev.genet.40.110405.090423
