This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
3f3v
From Proteopedia
| Line 1: | Line 1: | ||
| - | {{Seed}} | ||
[[Image:3f3v.png|left|200px]] | [[Image:3f3v.png|left|200px]] | ||
| - | <!-- | ||
| - | The line below this paragraph, containing "STRUCTURE_3f3v", creates the "Structure Box" on the page. | ||
| - | You may change the PDB parameter (which sets the PDB file loaded into the applet) | ||
| - | or the SCENE parameter (which sets the initial scene displayed when the page is loaded), | ||
| - | or leave the SCENE parameter empty for the default display. | ||
| - | --> | ||
{{STRUCTURE_3f3v| PDB=3f3v | SCENE= }} | {{STRUCTURE_3f3v| PDB=3f3v | SCENE= }} | ||
===Kinase domain of cSrc in complex with inhibitor RL45 (Type II)=== | ===Kinase domain of cSrc in complex with inhibitor RL45 (Type II)=== | ||
| - | |||
| - | <!-- | ||
| - | The line below this paragraph, {{ABSTRACT_PUBMED_19462975}}, adds the Publication Abstract to the page | ||
| - | (as it appears on PubMed at http://www.pubmed.gov), where 19462975 is the PubMed ID number. | ||
| - | --> | ||
{{ABSTRACT_PUBMED_19462975}} | {{ABSTRACT_PUBMED_19462975}} | ||
==About this Structure== | ==About this Structure== | ||
| - | + | [[3f3v]] is a 2 chain structure of [[Proto-oncogene tyrosine-protein kinase]] with sequence from [http://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3F3V OCA]. | |
| + | |||
| + | ==See Also== | ||
| + | *[[Proto-oncogene tyrosine-protein kinase|Proto-oncogene tyrosine-protein kinase]] | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:019462975</ref><references group="xtra"/> |
[[Category: Gallus gallus]] | [[Category: Gallus gallus]] | ||
[[Category: Non-specific protein-tyrosine kinase]] | [[Category: Non-specific protein-tyrosine kinase]] | ||
| Line 31: | Line 22: | ||
[[Category: Rauh, D.]] | [[Category: Rauh, D.]] | ||
[[Category: Allosteric]] | [[Category: Allosteric]] | ||
| - | [[Category: Alternative splicing]] | ||
[[Category: Atp-binding]] | [[Category: Atp-binding]] | ||
[[Category: Dfg-out]] | [[Category: Dfg-out]] | ||
| Line 45: | Line 35: | ||
[[Category: Type ii]] | [[Category: Type ii]] | ||
[[Category: Tyrosine-protein kinase]] | [[Category: Tyrosine-protein kinase]] | ||
| - | |||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jul 22 20:47:33 2009'' | ||
Revision as of 12:52, 26 July 2012
Contents |
Kinase domain of cSrc in complex with inhibitor RL45 (Type II)
Template:ABSTRACT PUBMED 19462975
About this Structure
3f3v is a 2 chain structure of Proto-oncogene tyrosine-protein kinase with sequence from Gallus gallus. Full crystallographic information is available from OCA.
See Also
Reference
- Getlik M, Grutter C, Simard JR, Kluter S, Rabiller M, Rode HB, Robubi A, Rauh D. Hybrid compound design to overcome the gatekeeper T338M mutation in cSrc. J Med Chem. 2009 Jul 9;52(13):3915-26. PMID:19462975 doi:10.1021/jm9002928
Categories: Gallus gallus | Non-specific protein-tyrosine kinase | Getlik, M. | Grutter, C. | Kluter, S. | Rauh, D. | Allosteric | Atp-binding | Dfg-out | Kinase | Lipoprotein | Myristate | Nucleotide-binding | Phosphoprotein | Proto-oncogene | Sh2 domain | Sh3 domain | Transferase | Type ii | Tyrosine-protein kinase
