3hp2

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'''Unreleased structure'''
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{{Seed}}
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[[Image:3hp2.jpg|left|200px]]
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The entry 3hp2 is ON HOLD until Paper Publication
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{{STRUCTURE_3hp2| PDB=3hp2 | SCENE= }}
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Authors: Shieh, H.-S., Williams, J.M., Stegeman, R.A., Kurumbail, R.G.
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===Crystal Structure of Human p38alpha complexed with a pyridinone compound===
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Description: Crystal Structure of Human p38alpha complexed with a pyridinone compound
 
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Aug 12 12:23:39 2009''
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{{ABSTRACT_PUBMED_19751974}}
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==About this Structure==
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3HP2 is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HP2 OCA].
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==Reference==
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<ref group="xtra">PMID:19751974</ref><references group="xtra"/>
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[[Category: Homo sapiens]]
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[[Category: Mitogen-activated protein kinase]]
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[[Category: Kurumbail, R G.]]
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[[Category: Shieh, H S.]]
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[[Category: Stegeman, R A.]]
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[[Category: Williams, J M.]]
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[[Category: Alternative splicing]]
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[[Category: Atp site and distal site]]
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[[Category: Atp-binding]]
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[[Category: Cytoplasm]]
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[[Category: Kinase]]
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[[Category: Nucleotide-binding]]
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[[Category: Nucleus]]
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[[Category: Peptide flip]]
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[[Category: Phosphoprotein]]
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[[Category: Polymorphism]]
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[[Category: Serine/threonine-protein kinase]]
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[[Category: Transferase]]
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[[Category: Two binding site]]
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[[Category: Two ligand]]
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[[Category: Two lobe]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Sep 30 09:11:25 2009''

Revision as of 07:11, 30 September 2009

Image:3hp2.jpg

Template:STRUCTURE 3hp2

Crystal Structure of Human p38alpha complexed with a pyridinone compound

Template:ABSTRACT PUBMED 19751974

About this Structure

3HP2 is a 1 chain structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Selness SR, Devraj RV, Monahan JB, Boehm TL, Walker JK, Devadas B, Durley RC, Kurumbail R, Shieh H, Xing L, Hepperle M, Rucker PV, Jerome KD, Benson AG, Marrufo LD, Madsen HM, Hitchcock J, Owen TJ, Christie L, Promo MA, Hickory BS, Alvira E, Naing W, Blevis-Bal R. Discovery of N-substituted pyridinones as potent and selective inhibitors of p38 kinase. Bioorg Med Chem Lett. 2009 Oct 15;19(20):5851-6. Epub 2009 Aug 27. PMID:19751974 doi:10.1016/j.bmcl.2009.08.082

Page seeded by OCA on Wed Sep 30 09:11:25 2009

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