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3ggu

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==About this Structure==
==About this Structure==
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3GGU is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Viruses Viruses]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GGU OCA].
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[[3ggu]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Viruses Viruses]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GGU OCA].
==Reference==
==Reference==
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[[Category: Rezacova, P.]]
[[Category: Rezacova, P.]]
[[Category: Saskova, K G.]]
[[Category: Saskova, K G.]]
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[[Category: Darunvir]]
 
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[[Category: Hiv protease]]
 
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[[Category: Hydrolase]]
 
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[[Category: Mutation score]]
 
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[[Category: Resistance]]
 
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[[Category: Tmc-114]]
 
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Aug 12 12:35:34 2009''
 

Revision as of 04:46, 16 February 2011

Image:3ggu.png


PDB ID 3ggu

Drag the structure with the mouse to rotate
3ggu, resolution 1.80Å ()
Ligands:
Gene: Gag-Pol, pol (Viruses)
Activity: HIV-1 retropepsin, with EC number 3.4.23.16
Related: 3ggt
Resources: FirstGlance, OCA, PDBsum, RCSB
Coordinates: save as pdb, mmCIF, xml



HIV PR drug resistant patient's variant in complex with darunavir

Template:ABSTRACT PUBMED 19535439

About this Structure

3ggu is a 2 chain structure with sequence from Viruses. Full crystallographic information is available from OCA.

Reference

  • Saskova KG, Kozisek M, Rezacova P, Brynda J, Yashina T, Kagan RM, Konvalinka J. Molecular characterization of clinical isolates of human immunodeficiency virus resistant to the protease inhibitor darunavir. J Virol. 2009 Sep;83(17):8810-8. Epub 2009 Jun 17. PMID:19535439 doi:10.1128/JVI.00451-09

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