2wpa

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'''Unreleased structure'''
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{{Seed}}
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[[Image:2wpa.jpg|left|200px]]
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The entry 2wpa is ON HOLD until Paper Publication
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{{STRUCTURE_2wpa| PDB=2wpa | SCENE= }}
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Authors: Brasca, M.G., Albanese, C., Alzani, R., Amici, R., Avanzi, N., Ballinari, D., Bischoff, J., Borghi, D., Casale, E., Croci, V., Fiorentini, F., Isacchi, A., Mercurio, C., Nesi, M., Orsini, P., Pastori, W., Pesenti, E., Pevarello, P., Roussel, P., Varasi, M., Volpi, D., Vulpetti, A., Ciomei, M.
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===OPTIMISATION OF 6,6-DIMETHYL PYRROLO 3,4-C PYRAZOLES: IDENTIFICATION OF PHA-793887, A POTENT CDK INHIBITOR SUITABLE FOR INTRAVENOUS DOSING===
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Description: Optimisation of 6,6-Dimethyl Pyrrolo 3,4-c pyrazoles: Identification of PHA-793887, a Potent CDK Inhibitor Suitable for Intravenous Dosing
 
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Aug 19 12:23:31 2009''
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{{ABSTRACT_PUBMED_20153204}}
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==About this Structure==
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2WPA is a 4 chains structure with sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WPA OCA].
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==Reference==
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<ref group="xtra">PMID:20153204</ref><references group="xtra"/>
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[[Category: Homo sapiens]]
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[[Category: Non-specific serine/threonine protein kinase]]
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[[Category: Albanese, C.]]
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[[Category: Alzani, R.]]
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[[Category: Amici, R.]]
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[[Category: Avanzi, N.]]
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[[Category: Ballinari, D.]]
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[[Category: Bischoff, J.]]
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[[Category: Borghi, D.]]
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[[Category: Brasca, M G.]]
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[[Category: Casale, E.]]
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[[Category: Ciomei, M.]]
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[[Category: Croci, V.]]
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[[Category: Fiorentini, F.]]
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[[Category: Isacchi, A.]]
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[[Category: Mercurio, C.]]
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[[Category: Nesi, M.]]
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[[Category: Orsini, P.]]
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[[Category: Pastori, W.]]
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[[Category: Pesenti, E.]]
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[[Category: Pevarello, P.]]
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[[Category: Roussel, P.]]
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[[Category: Varasi, M.]]
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[[Category: Volpi, D.]]
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[[Category: Vulpetti, A.]]
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[[Category: Atp-binding]]
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[[Category: Cell cycle]]
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[[Category: Cyclin]]
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[[Category: Mitosis]]
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[[Category: Phosphoprotein]]
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[[Category: Serine/threonine-protein 2 kinase]]
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[[Category: Transferase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 25 13:28:46 2010''

Revision as of 11:28, 25 February 2010

Image:2wpa.jpg

Template:STRUCTURE 2wpa

OPTIMISATION OF 6,6-DIMETHYL PYRROLO 3,4-C PYRAZOLES: IDENTIFICATION OF PHA-793887, A POTENT CDK INHIBITOR SUITABLE FOR INTRAVENOUS DOSING

Template:ABSTRACT PUBMED 20153204

About this Structure

2WPA is a 4 chains structure with sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Brasca MG, Albanese C, Alzani R, Amici R, Avanzi N, Ballinari D, Bischoff J, Borghi D, Casale E, Croci V, Fiorentini F, Isacchi A, Mercurio C, Nesi M, Orsini P, Pastori W, Pesenti E, Pevarello P, Roussel P, Varasi M, Volpi D, Vulpetti A, Ciomei M. Optimization of 6,6-dimethyl pyrrolo[3,4-c]pyrazoles: Identification of PHA-793887, a potent CDK inhibitor suitable for intravenous dosing. Bioorg Med Chem. 2010 Mar 1;18(5):1844-53. Epub 2010 Jan 25. PMID:20153204 doi:10.1016/j.bmc.2010.01.042

Page seeded by OCA on Thu Feb 25 13:28:46 2010

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