3e8n
From Proteopedia
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===X-ray structure of the human mitogen-activated protein kinase kinase 1 (MEK1) complexed with a potent inhibitor RDEA119 and MgATP=== | ===X-ray structure of the human mitogen-activated protein kinase kinase 1 (MEK1) complexed with a potent inhibitor RDEA119 and MgATP=== | ||
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{{ABSTRACT_PUBMED_19706763}} | {{ABSTRACT_PUBMED_19706763}} | ||
==About this Structure== | ==About this Structure== | ||
| - | + | [[3e8n]] is a 1 chain structure of [[Ephrin receptor]] and [[Mitogen-activated protein kinase kinase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3E8N OCA]. | |
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| + | ==See Also== | ||
| + | *[[Ephrin receptor|Ephrin receptor]] | ||
| + | *[[Mitogen-activated protein kinase kinase|Mitogen-activated protein kinase kinase]] | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:019706763</ref><references group="xtra"/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Mitogen-activated protein kinase kinase]] | [[Category: Mitogen-activated protein kinase kinase]] | ||
[[Category: Wang, Z M.]] | [[Category: Wang, Z M.]] | ||
[[Category: Yan, S.]] | [[Category: Yan, S.]] | ||
| - | [[Category: Acetylation]] | ||
[[Category: Atp-binding]] | [[Category: Atp-binding]] | ||
[[Category: Disease mutation]] | [[Category: Disease mutation]] | ||
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[[Category: Transferase]] | [[Category: Transferase]] | ||
[[Category: Tyrosine-protein kinase]] | [[Category: Tyrosine-protein kinase]] | ||
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| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Sep 16 08:26:28 2009'' | ||
Revision as of 15:44, 26 July 2012
Contents |
X-ray structure of the human mitogen-activated protein kinase kinase 1 (MEK1) complexed with a potent inhibitor RDEA119 and MgATP
Template:ABSTRACT PUBMED 19706763
About this Structure
3e8n is a 1 chain structure of Ephrin receptor and Mitogen-activated protein kinase kinase with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Iverson C, Larson G, Lai C, Yeh LT, Dadson C, Weingarten P, Appleby T, Vo T, Maderna A, Vernier JM, Hamatake R, Miner JN, Quart B. RDEA119/BAY 869766: a potent, selective, allosteric inhibitor of MEK1/2 for the treatment of cancer. Cancer Res. 2009 Sep 1;69(17):6839-47. Epub 2009 Aug 25. PMID:19706763 doi:10.1158/0008-5472.CAN-09-0679
Categories: Homo sapiens | Mitogen-activated protein kinase kinase | Wang, Z M. | Yan, S. | Atp-binding | Disease mutation | Kinase | Mek1 | Mek1-rdea119 complex | Nucleotide-binding | Phosphoprotein | Protein kinase-ligand-mgatp complex | Rdea-119 | Rdea119 | Serine/threonine-protein kinase | Transferase | Tyrosine-protein kinase
