3iw4

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'''Unreleased structure'''
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{{Seed}}
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[[Image:3iw4.jpg|left|200px]]
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The entry 3iw4 is ON HOLD until Paper Publication
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{{STRUCTURE_3iw4| PDB=3iw4 | SCENE= }}
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Authors: Stark, W., Rummel, G., Strauss, A., Cowan-Jacob, S.W.
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===Crystal structure of PKC alpha in complex with NVP-AEB071===
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Description: Crystal structure of PKC alpha in complex with NVP-AEB071
 
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Sep 16 08:44:39 2009''
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The line below this paragraph, {{ABSTRACT_PUBMED_19827831}}, adds the Publication Abstract to the page
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(as it appears on PubMed at http://www.pubmed.gov), where 19827831 is the PubMed ID number.
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{{ABSTRACT_PUBMED_19827831}}
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==About this Structure==
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3IW4 is a 3 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IW4 OCA].
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==Reference==
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<ref group="xtra">PMID:19827831</ref><references group="xtra"/>
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[[Category: Homo sapiens]]
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[[Category: Protein kinase C]]
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[[Category: Cowan-Jacob, S W.]]
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[[Category: Rummel, G.]]
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[[Category: Stark, W.]]
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[[Category: Strauss, A.]]
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[[Category: Atp-binding]]
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[[Category: Calcium]]
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[[Category: Cell membrane]]
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[[Category: Cytoplasm]]
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[[Category: Kinase]]
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[[Category: Membrane]]
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[[Category: Metal-binding]]
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[[Category: Nucleotide-binding]]
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[[Category: Phorbol-ester binding]]
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[[Category: Phosphoprotein]]
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[[Category: Polymorphism]]
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[[Category: Serine/threonine-protein kinase]]
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[[Category: Transferase]]
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[[Category: Zinc]]
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[[Category: Zinc-finger]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Nov 4 11:01:42 2009''

Revision as of 09:01, 4 November 2009

Image:3iw4.jpg

Template:STRUCTURE 3iw4

Crystal structure of PKC alpha in complex with NVP-AEB071

Template:ABSTRACT PUBMED 19827831

About this Structure

3IW4 is a 3 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Wagner J, von Matt P, Sedrani R, Albert R, Cooke N, Ehrhardt C, Geiser M, Rummel G, Stark W, Strauss A, Cowan-Jacob SW, Beerli C, Weckbecker G, Evenou JP, Zenke G, Cottens S. Discovery of 3-(1H-indol-3-yl)-4-[2-(4-methylpiperazin-1-yl)quinazolin-4-yl]pyrrole-2,5 -dione (AEB071), a potent and selective inhibitor of protein kinase C isotypes. J Med Chem. 2009 Oct 22;52(20):6193-6. PMID:19827831 doi:10.1021/jm901108b

Page seeded by OCA on Wed Nov 4 11:01:42 2009

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