2wj2
From Proteopedia
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===3D-CRYSTAL STRUCTURE OF HUMANIZED-RAT FATTY ACID AMIDE HYDROLASE (FAAH) CONJUGATED WITH 7-PHENYL-1-(5-(PYRIDIN-2-YL)OXAZOL-2-YL)HEPTAN-1-ONE, AN ALPHA-KETOOXAZOLE=== | ===3D-CRYSTAL STRUCTURE OF HUMANIZED-RAT FATTY ACID AMIDE HYDROLASE (FAAH) CONJUGATED WITH 7-PHENYL-1-(5-(PYRIDIN-2-YL)OXAZOL-2-YL)HEPTAN-1-ONE, AN ALPHA-KETOOXAZOLE=== | ||
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{{ABSTRACT_PUBMED_19722626}} | {{ABSTRACT_PUBMED_19722626}} | ||
==About this Structure== | ==About this Structure== | ||
- | + | [[2wj2]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WJ2 OCA]. | |
==Reference== | ==Reference== | ||
- | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:019722626</ref><references group="xtra"/> |
[[Category: Amidase]] | [[Category: Amidase]] | ||
[[Category: Rattus norvegicus]] | [[Category: Rattus norvegicus]] | ||
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[[Category: Phosphoprotein]] | [[Category: Phosphoprotein]] | ||
[[Category: Transmembrane]] | [[Category: Transmembrane]] | ||
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- | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Sep 16 08:58:44 2009'' |
Revision as of 19:56, 7 January 2013
3D-CRYSTAL STRUCTURE OF HUMANIZED-RAT FATTY ACID AMIDE HYDROLASE (FAAH) CONJUGATED WITH 7-PHENYL-1-(5-(PYRIDIN-2-YL)OXAZOL-2-YL)HEPTAN-1-ONE, AN ALPHA-KETOOXAZOLE
Template:ABSTRACT PUBMED 19722626
About this Structure
2wj2 is a 2 chain structure with sequence from Rattus norvegicus. Full crystallographic information is available from OCA.
Reference
- Mileni M, Garfunkle J, DeMartino JK, Cravatt BF, Boger DL, Stevens RC. Binding and inactivation mechanism of a humanized fatty acid amide hydrolase by alpha-ketoheterocycle inhibitors revealed from cocrystal structures. J Am Chem Soc. 2009 Aug 5;131(30):10497-506. PMID:19722626 doi:10.1021/ja902694n
Categories: Amidase | Rattus norvegicus | Boger, D L. | Cravatt, B F. | Demartino, J K. | Garfunkle, J. | Mileni, M. | Stevens, R C. | Alpha-ketooxazole | Covalent reversible inhibitor | Endoplasmic reticulum | Fatty acid amide hydrolase | Golgi apparatus | Hydrolase | Membrane | Monotopic membrane protein | Phosphoprotein | Transmembrane