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2aw1

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[[Image:2aw1.png|left|200px]]
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{{STRUCTURE_2aw1| PDB=2aw1 | SCENE= }}
{{STRUCTURE_2aw1| PDB=2aw1 | SCENE= }}
===Carbonic anhydrase inhibitors: Valdecoxib binds to a different active site region of the human isoform II as compared to the structurally related cyclooxygenase II "selective" inhibitor Celecoxib===
===Carbonic anhydrase inhibitors: Valdecoxib binds to a different active site region of the human isoform II as compared to the structurally related cyclooxygenase II "selective" inhibitor Celecoxib===
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{{ABSTRACT_PUBMED_16290146}}
{{ABSTRACT_PUBMED_16290146}}
==About this Structure==
==About this Structure==
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2AW1 is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AW1 OCA].
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[[2aw1]] is a 1 chain structure of [[Carbonic anhydrase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AW1 OCA].
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==See Also==
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*[[Carbonic anhydrase|Carbonic anhydrase]]
==Reference==
==Reference==
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<ref group="xtra">PMID:16290146</ref><references group="xtra"/>
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<ref group="xtra">PMID:016290146</ref><references group="xtra"/>
[[Category: Carbonate dehydratase]]
[[Category: Carbonate dehydratase]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Lyase]]
[[Category: Lyase]]
[[Category: Protein-inhibitor complex]]
[[Category: Protein-inhibitor complex]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Sep 23 08:12:18 2009''
 

Revision as of 10:54, 25 July 2012

Template:STRUCTURE 2aw1

Contents

Carbonic anhydrase inhibitors: Valdecoxib binds to a different active site region of the human isoform II as compared to the structurally related cyclooxygenase II "selective" inhibitor Celecoxib

Template:ABSTRACT PUBMED 16290146

About this Structure

2aw1 is a 1 chain structure of Carbonic anhydrase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  • Di Fiore A, Pedone C, D'Ambrosio K, Scozzafava A, De Simone G, Supuran CT. Carbonic anhydrase inhibitors: Valdecoxib binds to a different active site region of the human isoform II as compared to the structurally related cyclooxygenase II "selective" inhibitor celecoxib. Bioorg Med Chem Lett. 2006 Jan 15;16(2):437-42. Epub 2005 Nov 14. PMID:16290146 doi:10.1016/j.bmcl.2005.09.040

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