This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


2zvt

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
-
'''Unreleased structure'''
+
{{Seed}}
 +
[[Image:2zvt.jpg|left|200px]]
-
The entry 2zvt is ON HOLD until Paper Publication
+
<!--
 +
The line below this paragraph, containing "STRUCTURE_2zvt", creates the "Structure Box" on the page.
 +
You may change the PDB parameter (which sets the PDB file loaded into the applet)
 +
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
 +
or leave the SCENE parameter empty for the default display.
 +
-->
 +
{{STRUCTURE_2zvt| PDB=2zvt | SCENE= }}
-
Authors: Waku, T., Oyama, T., Shiraki, T., Morikawa, K.
+
===Cys285Ser mutant PPARgamma ligand-binding domain complexed with 15-deoxy-delta12,14-prostaglandin J2===
-
Description: Cys285Ser mutant PPARgamma ligand-binding domain complexed with 15-deoxy-delta12,14-prostaglandin J2
 
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Dec 10 14:34:09 2008''
+
<!--
 +
The line below this paragraph, {{ABSTRACT_PUBMED_19101554}}, adds the Publication Abstract to the page
 +
(as it appears on PubMed at http://www.pubmed.gov), where 19101554 is the PubMed ID number.
 +
-->
 +
{{ABSTRACT_PUBMED_19101554}}
 +
 
 +
==Disease==
 +
Known disease associated with this structure: Carotid intimal medial thickness 1 OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=601487 601487]], Insulin resistance, severe, digenic OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=601487 601487]], Lipodystrophy, familial partial, type 3 OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=601487 601487]], Obesity, severe OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=601487 601487]], Obesity, resistance to OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=601487 601487]], Diabetes, type 2 OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=601487 601487]], Glioblastoma, susceptibility to OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=601487 601487]]
 +
 
 +
==About this Structure==
 +
2ZVT is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZVT OCA].
 +
 
 +
==Reference==
 +
<ref group="xtra">PMID:19101554</ref><references group="xtra"/>
 +
[[Category: Homo sapiens]]
 +
[[Category: Morikawa, K.]]
 +
[[Category: Oyama, T.]]
 +
[[Category: Shiraki, T.]]
 +
[[Category: Waku, T.]]
 +
[[Category: Activator]]
 +
[[Category: Alternative splicing]]
 +
[[Category: Anti parallel helix sandwich]]
 +
[[Category: Diabetes mellitus]]
 +
[[Category: Disease mutation]]
 +
[[Category: Dna-binding]]
 +
[[Category: Metal-binding]]
 +
[[Category: Nucleus]]
 +
[[Category: Obesity]]
 +
[[Category: Phosphoprotein]]
 +
[[Category: Polymorphism]]
 +
[[Category: Receptor]]
 +
[[Category: Transcription]]
 +
[[Category: Transcription regulation]]
 +
[[Category: Zinc]]
 +
[[Category: Zinc-finger]]
 +
 
 +
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Oct 7 13:53:39 2009''

Revision as of 11:53, 7 October 2009

Image:2zvt.jpg

Template:STRUCTURE 2zvt

Contents

Cys285Ser mutant PPARgamma ligand-binding domain complexed with 15-deoxy-delta12,14-prostaglandin J2

Template:ABSTRACT PUBMED 19101554

Disease

Known disease associated with this structure: Carotid intimal medial thickness 1 OMIM:[601487], Insulin resistance, severe, digenic OMIM:[601487], Lipodystrophy, familial partial, type 3 OMIM:[601487], Obesity, severe OMIM:[601487], Obesity, resistance to OMIM:[601487], Diabetes, type 2 OMIM:[601487], Glioblastoma, susceptibility to OMIM:[601487]

About this Structure

2ZVT is a 2 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Waku T, Shiraki T, Oyama T, Morikawa K. Atomic structure of mutant PPARgamma LBD complexed with 15d-PGJ2: novel modulation mechanism of PPARgamma/RXRalpha function by covalently bound ligands. FEBS Lett. 2009 Jan 22;583(2):320-4. Epub 2008 Dec 26. PMID:19101554 doi:10.1016/j.febslet.2008.12.017

Page seeded by OCA on Wed Oct 7 13:53:39 2009

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/2zvt"
Personal tools