3idp

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'''Unreleased structure'''
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{{Seed}}
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[[Image:3idp.jpg|left|200px]]
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The entry 3idp is ON HOLD until Paper Publication
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{{STRUCTURE_3idp| PDB=3idp | SCENE= }}
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Authors: Whittington, D.A., Epstein, L.F.
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===B-Raf V600E kinase domain in complex with an aminoisoquinoline inhibitor===
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Description: B-Raf V600E kinase domain in complex with an aminoisoquinoline inhibitor
 
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Aug 19 12:35:07 2009''
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{{ABSTRACT_PUBMED_19764794}}
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==About this Structure==
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3IDP is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IDP OCA].
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==Reference==
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<ref group="xtra">PMID:19764794</ref><references group="xtra"/>
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[[Category: Homo sapiens]]
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[[Category: Non-specific serine/threonine protein kinase]]
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[[Category: Epstein, L F.]]
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[[Category: Whittington, D A.]]
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[[Category: Acetylation]]
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[[Category: Atp-binding]]
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[[Category: Cardiomyopathy]]
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[[Category: Cytoplasm]]
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[[Category: Dfg-out]]
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[[Category: Disease mutation]]
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[[Category: Kinase]]
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[[Category: Metal-binding]]
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[[Category: Nucleotide-binding]]
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[[Category: Oncogene]]
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[[Category: Phorbol-ester binding]]
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[[Category: Phosphoprotein]]
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[[Category: Polymorphism]]
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[[Category: Proto-oncogene]]
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[[Category: Serine/threonine-protein kinase]]
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[[Category: Transferase]]
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[[Category: Zinc]]
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[[Category: Zinc-finger]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Oct 7 13:56:38 2009''

Revision as of 11:56, 7 October 2009

Image:3idp.jpg

Template:STRUCTURE 3idp

B-Raf V600E kinase domain in complex with an aminoisoquinoline inhibitor

Template:ABSTRACT PUBMED 19764794

About this Structure

3IDP is a 2 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Smith AL, Demorin FF, Paras NA, Huang Q, Petkus JK, Doherty EM, Nixey T, Kim JL, Whittington DA, Epstein LF, Lee MR, Rose MJ, Babij C, Fernando M, Hess K, Le Q, Beltran P, Carnahan J. Selective Inhibitors of the Mutant B-Raf Pathway: Discovery of a Potent and Orally Bioavailable Aminoisoquinoline. J Med Chem. 2009 Sep 18. PMID:19764794 doi:10.1021/jm901081g

Page seeded by OCA on Wed Oct 7 13:56:38 2009

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