2kj0

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'''Unreleased structure'''
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{{Seed}}
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[[Image:2kj0.jpg|left|200px]]
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The entry 2kj0 is ON HOLD until Paper Publication
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{{STRUCTURE_2kj0| PDB=2kj0 | SCENE= }}
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Authors: Hsu, S., Varnai, P., Bugaut, A., Reska, T., Neidle, S., Balasubramanian, S.
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===DNA promoter sequence of the c-kit oncogene forms a parallel G-quadruplex (c-kit2) with a long loop that confers asymmetric internal dynamics in the G-tetrads===
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Description: DNA promoter sequence of the c-kit oncogene forms a parallel G-quadruplex (c-kit2) with a long loop that confers asymmetric internal dynamics in the G-tetrads
 
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Aug 5 09:29:28 2009''
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The line below this paragraph, {{ABSTRACT_PUBMED_19705869}}, adds the Publication Abstract to the page
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(as it appears on PubMed at http://www.pubmed.gov), where 19705869 is the PubMed ID number.
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{{ABSTRACT_PUBMED_19705869}}
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==About this Structure==
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2KJ0 is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KJ0 OCA].
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==Reference==
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<ref group="xtra">PMID:19705869</ref><ref group="xtra">PMID:16784237</ref><references group="xtra"/>
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[[Category: Balasubramanian, S.]]
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[[Category: Bugaut, A.]]
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[[Category: Hsu, S.]]
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[[Category: Neidle, S.]]
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[[Category: Reska, T.]]
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[[Category: Varnai, P.]]
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[[Category: C-kit2]]
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[[Category: Dna]]
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[[Category: G-quadruplex]]
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[[Category: Oncogene]]
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[[Category: Promoter]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Oct 14 10:25:31 2009''

Revision as of 08:25, 14 October 2009

Image:2kj0.jpg

Template:STRUCTURE 2kj0

DNA promoter sequence of the c-kit oncogene forms a parallel G-quadruplex (c-kit2) with a long loop that confers asymmetric internal dynamics in the G-tetrads

Template:ABSTRACT PUBMED 19705869

About this Structure

2KJ0 is a 1 chain structure. Full experimental information is available from OCA.

Reference

  • Hsu ST, Varnai P, Bugaut A, Reszka AP, Neidle S, Balasubramanian S. A G-rich sequence within the c-kit oncogene promoter forms a parallel G-quadruplex having asymmetric G-tetrad dynamics. J Am Chem Soc. 2009 Sep 23;131(37):13399-409. PMID:19705869 doi:10.1021/ja904007p
  • Fernando H, Reszka AP, Huppert J, Ladame S, Rankin S, Venkitaraman AR, Neidle S, Balasubramanian S. A conserved quadruplex motif located in a transcription activation site of the human c-kit oncogene. Biochemistry. 2006 Jun 27;45(25):7854-60. PMID:16784237 doi:10.1021/bi0601510

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