2gqg
From Proteopedia
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[[Category: Klei, H E.]] | [[Category: Klei, H E.]] | ||
[[Category: Kinase]] | [[Category: Kinase]] | ||
| + | [[Category: Transferase]] | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Oct 21 09:34:36 2009'' |
Revision as of 07:34, 21 October 2009
X-ray Crystal Structure of Dasatinib (BMS-354825) Bound to Activated ABL Kinase Domain
Template:ABSTRACT PUBMED 16740718
About this Structure
2GQG is a 2 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Tokarski JS, Newitt JA, Chang CY, Cheng JD, Wittekind M, Kiefer SE, Kish K, Lee FY, Borzillerri R, Lombardo LJ, Xie D, Zhang Y, Klei HE. The structure of Dasatinib (BMS-354825) bound to activated ABL kinase domain elucidates its inhibitory activity against imatinib-resistant ABL mutants. Cancer Res. 2006 Jun 1;66(11):5790-7. PMID:16740718 doi:66/11/5790
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