3g6w

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Revision as of 07:48, 21 October 2009

Image:3g6w.png

Template:STRUCTURE 3g6w

Asymetric GTP bound structure of UPRTase from Sulfolobus solfataricus containing PRPP-mg2+ in half of the active sites and R5P and PPi in the other half

Template:ABSTRACT PUBMED 19683539

About this Structure

3G6W is a 4 chains structure of sequences from Sulfolobus solfataricus. Full crystallographic information is available from OCA.

Reference

  • Christoffersen S, Kadziola A, Johansson E, Rasmussen M, Willemoes M, Jensen KF. Structural and kinetic studies of the allosteric transition in Sulfolobus solfataricus uracil phosphoribosyltransferase: Permanent activation by engineering of the C-terminus. J Mol Biol. 2009 Oct 23;393(2):464-77. Epub 2009 Aug 14. PMID:19683539 doi:10.1016/j.jmb.2009.08.019
  • Arent S, Harris P, Jensen KF, Larsen S. Allosteric regulation and communication between subunits in uracil phosphoribosyltransferase from Sulfolobus solfataricus. Biochemistry. 2005 Jan 25;44(3):883-92. PMID:15654744 doi:10.1021/bi048041l

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