3jsm

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Revision as of 07:49, 21 October 2009

Image:3jsm.png

Template:STRUCTURE 3jsm

K65R mutant HIV-1 reverse transcriptase cross-linked to DS-DNA and complexed with tenofovir-diphosphate as the incoming nucleotide substrate

About this Structure

3JSM is a 4 chains structure of sequences from Human immunodeficiency virus type 1 bh10. Full crystallographic information is available from OCA.

Reference

  • Tuske S, Sarafianos SG, Clark AD Jr, Ding J, Naeger LK, White KL, Miller MD, Gibbs CS, Boyer PL, Clark P, Wang G, Gaffney BL, Jones RA, Jerina DM, Hughes SH, Arnold E. Structures of HIV-1 RT-DNA complexes before and after incorporation of the anti-AIDS drug tenofovir. Nat Struct Mol Biol. 2004 May;11(5):469-74. Epub 2004 Apr 25. PMID:15107837 doi:10.1038/nsmb760

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