3i53

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Revision as of 07:53, 21 October 2009

Image:3i53.png

Template:STRUCTURE 3i53

Crystal structure of an O-methyltransferase (NcsB1) from neocarzinostatin biosynthesis in complex with S-adenosyl-L-homocysteine (SAH)

Template:ABSTRACT PUBMED 19702337

About this Structure

3I53 is a 2 chains structure of sequences from Streptomyces carzinostaticus subsp. neocarzinostaticus. Full crystallographic information is available from OCA.

Reference

  • Cooke HA, Guenther EL, Luo Y, Shen B, Bruner SD. Molecular basis of substrate promiscuity for the SAM-dependent O-methyltransferase NcsB1, involved in the biosynthesis of the enediyne antitumor antibiotic neocarzinostatin. Biochemistry. 2009 Aug 25. PMID:19702337 doi:10.1021/bi901257q

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