1d96
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(New page: 200px<br /><applet load="1d96" size="450" color="white" frame="true" align="right" spinBox="true" caption="1d96, resolution 2.000Å" /> '''MOLECULAR STRUCTURE...)
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Revision as of 00:40, 25 November 2007
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MOLECULAR STRUCTURE OF R(GCG)D(TATACGC): A DNA-RNA HYBRID HELIX JOINED TO DOUBLE HELICAL DNA
Overview
The molecule r(GCG)d(TATACGC) is self-complementary and forms two DNA--RNA, hybrid segments surrounding a central region of double helical DNA; its, molecular structure has been solved by X-ray analysis. All three parts of, the molecule adopt a conformation which is close to that seen in the, 11-fold RNA double helix. The conformation of the ribonucleotides is, partly determined by water molecules bridging between the ribose O2', hydroxyl group and cytosine O2. The hybrid-DNA duplex junction contains no, structural discontinuities. However, the central DNA TATA sequence has, some structural irregularities.
About this Structure
1D96 is a Protein complex structure of sequences from [1]. Full crystallographic information is available from OCA.
Reference
Molecular structure of r(GCG)d(TATACGC): a DNA--RNA hybrid helix joined to double helical DNA., Wang AH, Fujii S, van Boom JH, van der Marel GA, van Boeckel SA, Rich A, Nature. 1982 Oct 14;299(5884):601-4. PMID:6181416
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