1gi7
From Proteopedia
(Difference between revisions)
| Line 42: | Line 42: | ||
[[Category: Verner, E.]] | [[Category: Verner, E.]] | ||
[[Category: Young, W.]] | [[Category: Young, W.]] | ||
| + | [[Category: Blood clotting]] | ||
| + | [[Category: Hydrolase]] | ||
[[Category: Oxyanion hole water]] | [[Category: Oxyanion hole water]] | ||
[[Category: Shift of pka of his57]] | [[Category: Shift of pka of his57]] | ||
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[[Category: Zn+2-mediated inhibition]] | [[Category: Zn+2-mediated inhibition]] | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Nov 4 11:07:57 2009'' |
Revision as of 09:08, 4 November 2009
A NOVEL SERINE PROTEASE INHIBITION MOTIF INVOLVING A MULTI-CENTERED SHORT HYDROGEN BONDING NETWORK AT THE ACTIVE SITE
Template:ABSTRACT PUBMED 11292354
About this Structure
1GI7 is a 2 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Katz BA, Elrod K, Luong C, Rice MJ, Mackman RL, Sprengeler PA, Spencer J, Hataye J, Janc J, Link J, Litvak J, Rai R, Rice K, Sideris S, Verner E, Young W. A novel serine protease inhibition motif involving a multi-centered short hydrogen bonding network at the active site. J Mol Biol. 2001 Apr 13;307(5):1451-86. PMID:11292354 doi:http://dx.doi.org/10.1006/jmbi.2001.4516
Page seeded by OCA on Wed Nov 4 11:07:57 2009
Categories: Homo sapiens | U-plasminogen activator | Elrod, K. | Hatayte, J. | Janc, J. | Katz, B A. | Link, J. | Litvak, J. | Luong, C. | Mackman, R L. | Rai, R. | Rice, K. | Rice, M. | Sideris, S. | Spencer, J. | Sprengeler, P A. | Verner, E. | Young, W. | Blood clotting | Hydrolase | Oxyanion hole water | Shift of pka of his57 | Specificity | Structure-based drug design | Three-centered | Thrombin | Trypsin | Urokinase | Very short hydrogen bond | Zn+2-mediated inhibition
